The multifactorial nature of healthy brain ageing: Brain changes, functional decline and protective factors

S Turrini, B Wong, M Eldaief, DZ Press… - Ageing Research …, 2023 - Elsevier
As the global population faces a progressive shift towards a higher median age,
understanding the mechanisms underlying healthy brain ageing has become of paramount …

Simulation-based inference on virtual brain models of disorders

M Hashemi, A Ziaeemehr, MM Woodman… - Machine Learning …, 2024 - iopscience.iop.org
Connectome-based models, also known as virtual brain models (VBMs), have been well
established in network neuroscience to investigate pathophysiological causes underlying a …

Pathologic substrates of structural brain network resilience and topology in Parkinson disease decedents

I Frigerio, TAA Broeders, CP Lin, MMA Bouwman… - Neurology, 2024 - neurology.org
Background and Objectives In Parkinson disease (PD), α-synuclein spreading through
connected brain regions leads to neuronal loss and brain network disruptions. With diffusion …

Genetic fingerprinting with heritable phenotypes of the resting-state brain network topology

H Pourmotabbed, DF Clarke, C Chang… - Communications …, 2024 - nature.com
Cognitive, behavioral, and disease traits are influenced by both genetic and environmental
factors. Individual differences in these traits have been associated with graph theoretical …

[HTML][HTML] Exploring the link between brain topological resilience and cognitive performance in the context of aging and vascular risk factors: A cross-ethnicity population …

H Liu, J **g, J Jiang, W Wen, W Zhu, Z Li, Y Pan, X Cai… - Science Bulletin, 2024 - Elsevier
Brain aging is typically associated with a significant decline in cognitive performance.
Vascular risk factors and subsequent atherosclerosis play a major role in this process. Brain …

[HTML][HTML] Frontoparietal pattern similarity analyses of cognitive control in monozygotic twins

R Tang, JA Etzel, A Kizhner, TS Braver - NeuroImage, 2021 - Elsevier
The ability to flexibly adapt thoughts and actions in a goal-directed manner appears to rely
on cognitive control mechanisms that are strongly impacted by individual differences. A …

Probabilistic Inference on Virtual Brain Models of Disorders

M Hashemi, A Ziaeemehr, MM Woodman, S Petkoski… - bioRxiv, 2024 - biorxiv.org
Connectome-based models, also known as Virtual Brain Models (VBMs), have been well
established in network neuroscience to investigate pathophysiological causes underlying a …

The Resilience and Vulnerability of Human Brain Networks Across the Lifespan

P Shu, H Zhu, W **, J Zhou, S Tong… - IEEE Transactions on …, 2021 - ieeexplore.ieee.org
Resilience, the ability for a system to maintain its basic functionality when suffering from
lesions, is a critical property for human brain, especially in the brain aging process. This …

Topographical functional correlates of interindividual differences in executive functions in young healthy twins

A Menardi, AE Reineberg, LL Smith… - Brain Structure and …, 2022 - Springer
Executive functions (EF) are a set of higher-order cognitive abilities that enable goal-
directed behavior by controlling lower-level operations. In the brain, those functions have …

Functional Hippocampal Redundancy as a Measure of Resilience to Pathological Aging

S Langella - 2021 - search.proquest.com
Aging is accompanied by declines in episodic memory and altered hippocampal function,
each of which are exacerbated in response to the development of Alzheimer's disease …