Bridging biological cfDNA features and machine learning approaches

T Moser, S Kühberger, I Lazzeri, G Vlachos, E Heitzer - Trends in Genetics, 2023 - cell.com
Liquid biopsies (LBs), particularly using circulating tumor DNA (ctDNA), are expected to
revolutionize precision oncology and blood-based cancer screening. Recent technological …

Non-invasive biomarkers for early detection of breast cancer

J Li, X Guan, Z Fan, LM Ching, Y Li, X Wang, WM Cao… - Cancers, 2020 - mdpi.com
Simple Summary Early diagnosis of breast cancer greatly increases the chance of cure and
survival from the disease. The mammogram is widely used for early detection of breast …

Artificial intelligence in surveillance, diagnosis, drug discovery and vaccine development against COVID-19

G Arora, J Joshi, RS Mandal, N Shrivastava, R Virmani… - Pathogens, 2021 - mdpi.com
As of August 6th, 2021, the World Health Organization has notified 200.8 million laboratory-
confirmed infections and 4.26 million deaths from COVID-19, making it the worst pandemic …

Machine learning protocols in early cancer detection based on liquid biopsy: a survey

L Liu, X Chen, OO Petinrin, W Zhang, S Rahaman… - Life, 2021 - mdpi.com
With the advances of liquid biopsy technology, there is increasing evidence that body fluid
such as blood, urine, and saliva could harbor the potential biomarkers associated with tumor …

Magnetic particles for advanced molecular diagnosis

C Chircov, AM Grumezescu, AM Holban - Materials, 2019 - mdpi.com
Molecular diagnosis is the field that aims to develop nucleic-acid-based analytical methods
for biological markers and gene expression assessments by combining laboratory medicine …

[HTML][HTML] Liquid Biopsy in Pancreatic Ductal Adenocarcinoma: A Review of Methods and Applications

G Dubrovsky, A Ross, P Jalali, M Lotze - International Journal of …, 2024 - mdpi.com
Pancreatic ductal adenocarcinoma (PDAC) remains a malignancy with one of the highest
mortality rates. One limitation in the diagnosis and treatment of PDAC is the lack of an early …

Anthem: a user customised tool for fast and accurate prediction of binding between peptides and HLA class I molecules

S Mei, F Li, D **ang, R Ayala, P Faridi… - Briefings in …, 2021 - academic.oup.com
Neopeptide-based immunotherapy has been recognised as a promising approach for the
treatment of cancers. For neopeptides to be recognised by CD8+ T cells and induce an …

DEcancer: Machine learning framework tailored to liquid biopsy based cancer detection and biomarker signature selection

A Halner, L Hankey, Z Liang, F Pozzetti, DA Szulc, E Mi… - Iscience, 2023 - cell.com
Cancer is a leading cause of mortality worldwide. Over 50% of cancers are diagnosed late,
rendering many treatments ineffective. Existing liquid biopsy studies demonstrate a …

Mortality prediction of various cancer patients via relevant feature analysis and machine learning

C Bozkurt, T Aşuroğlu - SN Computer Science, 2023 - Springer
Breast, lung, prostate, and stomach cancers are the most frequent cancer types globally.
Early-stage detection and diagnosis of these cancers pose a challenge in the literature …

Noninvasive early diagnosis of intestinal diseases based on artificial intelligence in genomics and microbiome

W Zhang, X Chen, KC Wong - Journal of Gastroenterology and …, 2021 - Wiley Online Library
The maturing development in artificial intelligence (AI) and genomics has propelled the
advances in intestinal diseases including intestinal cancer, inflammatory bowel disease …