Bacillus sp. as a microbial cell factory: Advancements and future prospects
Bacillus sp. is one of the most distinctive gram-positive bacteria, able to grow efficiently
using cheap carbon sources and secrete a variety of useful substances, which are widely …
using cheap carbon sources and secrete a variety of useful substances, which are widely …
Production of proteins and commodity chemicals using engineered Bacillus subtilis platform strain
Currently, increasing demand of biochemicals produced from renewable resources has
motivated researchers to seek microbial production strategies instead of traditional chemical …
motivated researchers to seek microbial production strategies instead of traditional chemical …
The silkworm (Bombyx mori) gut microbiota is involved in metabolic detoxification by glucosylation of plant toxins
S Yuan, Y Sun, W Chang, J Zhang, J Sang… - Communications …, 2023 - nature.com
Herbivores have evolved the ability to detoxify feed components through different
mechanisms. The oligophagous silkworm feeds on Cudrania tricuspidata leaves (CTLs) …
mechanisms. The oligophagous silkworm feeds on Cudrania tricuspidata leaves (CTLs) …
iModulonDB: a knowledgebase of microbial transcriptional regulation derived from machine learning
Independent component analysis (ICA) of bacterial transcriptomes has emerged as a
powerful tool for obtaining co-regulated, independently-modulated gene sets (iModulons) …
powerful tool for obtaining co-regulated, independently-modulated gene sets (iModulons) …
High-resolution temporal profiling of E. coli transcriptional response
Understanding how cells dynamically adapt to their environment is a primary focus of
biology research. Temporal information about cellular behavior is often limited by both small …
biology research. Temporal information about cellular behavior is often limited by both small …
Pulcherriminic acid modulates iron availability and protects against oxidative stress during microbial interactions
V Charron-Lamoureux, L Haroune… - Nature …, 2023 - nature.com
Siderophores are soluble or membrane-embedded molecules that bind the oxidized form of
iron, Fe (III), and play roles in iron acquisition by microorganisms. Fe (III)-bound …
iron, Fe (III), and play roles in iron acquisition by microorganisms. Fe (III)-bound …
Machine-learning from Pseudomonas putida KT2440 transcriptomes reveals its transcriptional regulatory network
Bacterial gene expression is orchestrated by numerous transcription factors (TFs).
Elucidating how gene expression is regulated is fundamental to understanding bacterial …
Elucidating how gene expression is regulated is fundamental to understanding bacterial …
Adaptive laboratory evolution and independent component analysis disentangle complex vancomycin adaptation trajectories
Human infections with methicillin-resistant Staphylococcus aureus (MRSA) are commonly
treated with vancomycin, and strains with decreased susceptibility, designated as …
treated with vancomycin, and strains with decreased susceptibility, designated as …
Optimal dimensionality selection for independent component analysis of transcriptomic data
Background Independent component analysis is an unsupervised machine learning
algorithm that separates a set of mixed signals into a set of statistically independent source …
algorithm that separates a set of mixed signals into a set of statistically independent source …
Machine learning reveals the transcriptional regulatory network and circadian dynamics of Synechococcus elongatus PCC 7942
Synechococcus elongatus is an important cyanobacterium that serves as a versatile and
robust model for studying circadian biology and photosynthetic metabolism. Its …
robust model for studying circadian biology and photosynthetic metabolism. Its …