Polyploidy in Xenopus lowers metabolic rate by decreasing total cell surface area

C Cadart, J Bartz, G Oaks, MZ Liu, R Heald - Current Biology, 2023 - cell.com
Although polyploidization is frequent in development, cancer, and evolution, impacts on
animal metabolism are poorly understood. In Xenopus frogs, the number of genome copies …

Advancing genetic and genomic technologies deepen the pool for discovery in Xenopus tropicalis

A Kakebeen, A Wills - Developmental Dynamics, 2019 - Wiley Online Library
Xenopus laevis and Xenopus tropicalis have long been used to drive discovery in
developmental, cell, and molecular biology. These dual frog species boast experimental …

[HTML][HTML] Molecular conflicts disrupting centromere maintenance contribute to Xenopus hybrid inviability

M Kitaoka, OK Smith, AF Straight, R Heald - Current Biology, 2022 - cell.com
Although central to evolution, the causes of hybrid inviability that drive reproductive isolation
are poorly understood. Embryonic lethality occurs when the eggs of the frog X. tropicalis are …

Molecular conflicts disrupting centromere assembly contribute to Xenopus hybrid inviability

M Kitaoka, OK Smith, AF Straight, R Heald - bioRxiv, 2022 - biorxiv.org
Although central to evolution, the causes of hybrid inviability that drive reproductive isolation
are poorly understood. Embryonic lethality occurs when eggs of the frog X. tropicalis are …

The nuclear-cytoplasmic ratio controls the cell cycle period in compartmentalized frog egg extract

L Piñeros, N Frolov, D Ruiz-Reynés, A Van Eynde… - bioRxiv, 2024 - biorxiv.org
Each proliferating cell replicates its DNA and internal components before distributing this
material evenly to its daughters. Although the regulation of cyclin-dependent kinases (Cdks) …