Simple Summary Cancer metabolism is an emerging field of investigation aimed at
identifying cancer cell vulnerabilities in order to define novel anti-cancer therapeutic …

There is an increasing accumulation of data on the exceptional importance of mitochondria
in the occurrence and treatment of cancer, and in all lines of evidence for such participation …

Tumors reprogram their metabolism to generate complex neoplastic ecosystems. Here, we
demonstrate that glioblastoma (GBM) stem cells (GSCs) display elevated activity of the …

Primary mitochondrial diseases (PMDs) are associated with pediatric neurological disorders
and are traditionally related to oxidative phosphorylation system (OXPHOS) defects in …

Adaptation to chronic hypoxia occurs through changes in protein expression, which are
controlled by hypoxia-inducible factor 1α (HIF1α) and are necessary for cancer cell survival …

Myocardial ischemia‐reperfusion injury (MIRI) significantly worsens the outcomes of patients
with cardiovascular diseases. Dexmedetomidine (Dex) is recognized for its cardioprotective …

The oxidative tricarboxylic acid (TCA) cycle is a central mitochondrial pathway integrating
catabolic conversions of NAD+ to NADH and anabolic production of aspartate, a key amino …

Tissue‐engineered bone has emerged as a promising alternative for bone defect repair due
to the advantages of regenerative bone healing and physiological functional reconstruction …

Imbalanced osteogenic cell-mediated bone gain and osteoclastic remodeling accelerates
the development of osteoporosis, which is the leading risk factor of disability in the elderly …

Muscle stem cells (MuSCs) enable muscle growth and regeneration after exercise or injury,
but how metabolism controls their regenerative potential is poorly understood. We describe …