Medicinal properties of cannabinoids, terpenes, and flavonoids in cannabis, and benefits in migraine, headache, and pain: an update on current evidence and …

EP Baron - Headache: The Journal of Head and Face Pain, 2018 - Wiley Online Library
Background Comprehensive literature reviews of historical perspectives and evidence
supporting cannabis/cannabinoids in the treatment of pain, including migraine and …

Neuroprotective potential of limonene and limonene containing natural products

LB Eddin, NK Jha, MFN Meeran, KK Kesari, R Beiram… - Molecules, 2021 - mdpi.com
Limonene is a monoterpene confined to the family of Rutaceae, showing several biological
properties such as antioxidant, anti-inflammatory, anticancer, antinociceptive and …

Exploring Pharmacological Mechanisms of Lavender (Lavandula angustifolia) Essential Oil on Central Nervous System Targets

V López, B Nielsen, M Solas, MJ Ramírez… - Frontiers in …, 2017 - frontiersin.org
Lavender essential oil is traditionally used and approved by the European Medicines
Agency (EMA) as herbal medicine to relieve stress and anxiety. Some animal and clinical …

Patterns of medicinal cannabis use, strain analysis, and substitution effect among patients with migraine, headache, arthritis, and chronic pain in a medicinal cannabis …

EP Baron, P Lucas, J Eades, O Hogue - The journal of headache and pain, 2018 - Springer
Background Medicinal cannabis registries typically report pain as the most common reason
for use. It would be clinically useful to identify patterns of cannabis treatment in migraine and …

Review of toxicological assessment of d-limonene, a food and cosmetics additive

C Ravichandran, PC Badgujar, P Gundev… - Food and Chemical …, 2018 - Elsevier
Abstract R-(+)-limonene (d-limonene) is a commonly used flavor additive in food, beverages
and fragrances for its pleasant lemon-like odor. Considering its increasing applications, it's …

Anxiolytic effect of essential oils and their constituents: a review

N Zhang, L Yao - Journal of agricultural and food chemistry, 2019 - ACS Publications
Essential oils are usually used in aromatherapy to alleviate anxiety symptoms. In
comparison to traditional drugs, essential oils have fewer side effects and more diversified …

Terpenoids from cannabis do not mediate an entourage effect by acting at cannabinoid receptors

DB Finlay, KJ Sircombe, M Nimick, C Jones… - Frontiers in …, 2020 - frontiersin.org
The entourage effect was a proposed explanation for biological observations that
endocannabinoid ligand activities can be modified by other lipids released from cells at the …

Safety Evaluation And Risk Assessment Of d-Limonene

YW Kim, MJ Kim, BY Chung, DY Bang… - Journal of Toxicology …, 2013 - Taylor & Francis
d-Limonene, a major constituent of citrus oils, is a monoterpene widely used as a
flavor/fragrance additive in cosmetics, foods, and industrial solvents as it possesses a …

Anxiolytic-like effect of quercetin possibly through GABA receptor interaction pathway: In vivo and in silico studies

MS Islam, R Hossain, T Ahmed, MM Rahaman… - Molecules, 2022 - mdpi.com
Scientific evidence suggests that quercetin (QUR) has anxiolytic-like effects in experimental
animals. However, the mechanism of action responsible for its anxiolytic-like effects is yet to …

Evaluation of p-cymene, a natural antioxidant

TM de Oliveira, RBF de Carvalho… - Pharmaceutical …, 2015 - Taylor & Francis
Context: Several studies have demonstrated that essential oils and their major components
have antioxidant activity. p-Cymene is a monoterpene and a major constituent of essential …