[HTML][HTML] Leveraging knowledge of HDLs major protein ApoA1: Structure, function, mutations, and potential therapeutics

AS Bhale, K Venkataraman - Biomedicine & Pharmacotherapy, 2022 - Elsevier
Abstract Apolipoprotein A1 (ApoA1) is a member of the Apolipoprotein family of proteins. It's
a vital protein that helps in the production of high-density lipoprotein (HDL) particles, which …

Emerging role of HDL in brain cholesterol metabolism and neurodegenerative disorders

M Turri, C Marchi, MP Adorni, L Calabresi… - Biochimica et Biophysica …, 2022 - Elsevier
High-density lipoproteins (HDL) play a key role in cholesterol homeostasis maintenance in
the central nervous system (CNS), by carrying newly synthesized cholesterol from astrocytes …

Lactobacillus rhamnosus GG powder supplementation alleviates intestinal injury in piglets challenged by porcine epidemic diarrhea virus

Z Xu, Q Zhang, M Wu, Y Zhang, Z Li, H Li… - Frontiers in Cellular …, 2024 - frontiersin.org
Porcine epidemic diarrhea virus (PEDV) has become a challenging problem in pig industry
worldwide, causing significant profit losses. Lactobacillus rhamnosus GG (LGG) has been …

[HTML][HTML] Current development of molecular classifications of gastric cancer based on omics

Y Ma, Z Jiang, L Pan, Y Zhou… - International …, 2024 - spandidos-publications.com
Gastric cancer (GC) is a complex and heterogeneous disease with significant phenotypic
and genetic variation. Traditional classification systems rely mainly on the evaluation of …

CRISPR/Cas9-mediated knockout of APOC3 stabilizes plasma lipids and inhibits atherosclerosis in rabbits

Y Zha, Y Lu, T Zhang, K Yan, W Zhuang, J Liang… - Lipids in health and …, 2021 - Springer
Background High levels of apolipoprotein C3 (APOC3) can lead to hypertriglyceridemia,
which increases the risk of cardiovascular disease. We aim to create APOC3-knockout (KO) …

A Supramolecular Protein Assembly Intrinsically Rescues Memory Deficits in an Alzheimer's Disease Mouse Model

Y Hao, X Shen, J Liu, Z Cai, X Wang, Z Yang… - Nano Letters, 2024 - ACS Publications
Supramolecular protein assemblies have been used as intelligent drug delivery systems that
can encapsulate drugs and transport them to specific tissues or cells. However, the known …

HDL and LDL have distinct, opposing effects on LPS-induced brain inflammation

DE Radford-Smith, AG Yates, L Rizvi… - Lipids in health and …, 2023 - Springer
Endotoxemia and sepsis induce neuroinflammation and increase the risk of
neurodegenerative disorders although the mechanism by which peripheral infection leads to …

Effects of bisphenols on lipid metabolism and neuro–cardiovascular toxicity in marine medaka larvae

X Li, X He, X Lin, W Li, J Gao, N Zhang, Y Guo… - Aquatic Toxicology, 2023 - Elsevier
Bisphenols are environmental endocrine disruptors that have detrimental effects on aquatic
organisms. Using marine medaka larvae, this study explored the effects of bisphenol …

Sex-specific metabolic profiling to explain the increased CVD risk in women with migraine: A narrative review

FC Van Welie, LA Kreft, JMA Huisman… - The Journal of Headache …, 2023 - Springer
Background Migraine is a disabling neurological disorder whose diagnosis is based on
clinical criteria. A shortcoming of these criteria is that they do not fully capture the underlying …