Background Osteoporosis affects all sections of society, including families with people
affected by osteoporosis, government agencies and medical institutes in various fields. For …

Background A variety of mutations in the largest human gene, dystrophin, cause a spectrum
from mild to severe dystrophin-associated muscular dystrophies. Duchenne (DMD) and …

Background Rheumatoid arthritis (RA) has unclear pathogenesis, but the molecules that
feed its inflammatory state are known. Small interfering RNAs (siRNAs) are useful to identify …

The Achilles tendon is the thickest, strongest and largest tendon in the human body, but
despite its size and tensile strength, it frequently gets injured. Achilles tendon ruptures …

Tendinopathies are challenging conditions frequent in athletes and in middle-aged
overweight patients with no history of increased physical activity. The term “tendinopathy” …

Introduction Tendinopathies are common in elite and recreational athletes: traditionally
considered overuse injuries, they involve excessive tensile loading and subsequent …

Future human space missions to Mars and beyond may be realized for different research,
economic, political or survival reasons. Since space remains a hazardous environment for …

Hemoglobinopathies are monogenic disorders affecting hemoglobin synthesis. Thalassemia
and sickle cell disease (SCD) are considered the two major hemoglobinopathies …

Purpose: The authors investigated the association between risk of tendinopathies and
genetic markers in professional team sports. Methods: The authors studied 363 (mean [SD]; …

Background It is unclear what role COL1A1 polymorphisms play in anterior cruciate ligament
(ACL) injury pathophysiology. The present study investigated the relationship between …