Integrating gene annotation with orthology inference at scale

BM Kirilenko, C Munegowda, E Osipova, D Jebb… - Science, 2023 - science.org
Annotating coding genes and inferring orthologs are two classical challenges in genomics
and evolutionary biology that have traditionally been approached separately, limiting …

A comparative analysis of planarian genomes reveals regulatory conservation in the face of rapid structural divergence

M Ivanković, JN Brand, L Pandolfini, T Brown… - Nature …, 2024 - nature.com
The planarian Schmidtea mediterranea is being studied as a model species for
regeneration, but the assembly of planarian genomes remains challenging. Here, we report …

Next generation sequencing revolutionizes organismal biology research in bats

KM Garg, V Lamba, A Sanyal, P Dovih… - Journal of Molecular …, 2023 - Springer
The advent of next generation sequencing technologies (NGS) has greatly accelerated our
understanding of critical aspects of organismal biology from non-model organisms. Bats …

The evolution of sanguivory in vampire bats: origins and convergences

DK Riskin, GG Carter - Canadian Journal of Zoology, 2023 - cdnsciencepub.com
Blood-feeding (sanguivory) has evolved more than two dozen times among birds, fishes,
insects, arachnids, molluscs, crustaceans, and annelids; however, among mammals, it is …

[HTML][HTML] Co-option of an astacin metalloprotease is associated with an evolutionarily novel feeding morphology in a predatory nematode

Y Ishita, A Onodera, T Ekino, T Chihara… - Molecular Biology and …, 2023 - ncbi.nlm.nih.gov
Animals consume a wide variety of food sources to adapt to different environments.
However, the genetic mechanisms underlying the acquisition of evolutionarily novel feeding …

Vision-related convergent gene losses reveal SERPINE3's unknown role in the eye

H Indrischek, J Hammer, A Machate, N Hecker… - Elife, 2022 - elifesciences.org
Despite decades of research, knowledge about the genes that are important for
development and function of the mammalian eye and are involved in human eye disorders …

Vampire bats rapidly fuel running with essential or non-essential amino acids from a blood meal

GS Rossi, KC Welch Jr - Biology Letters, 2024 - royalsocietypublishing.org
In most mammals, running is fuelled by oxidization of endogenous carbohydrates and lipids
while amino acids contribute little (< 5–10%). Common vampire bats (Desmodus rotundus) …

Haplotype-resolved genome and population genomics of the threatened garden dormouse in Europe

PA Byerly, A von Thaden, E Leushkin… - Genome …, 2024 - genome.cshlp.org
Genomic resources are important for evaluating genetic diversity and supporting
conservation efforts. The garden dormouse (Eliomys quercinus) is a small rodent that has …

Bat genomes illuminate adaptations to viral tolerance and disease resistance

AE Morales, Y Dong, T Brown, K Baid, DG Kontopoulos… - Nature, 2025 - nature.com
Zoonoses are infectious diseases transmitted from animals to humans. Bats have been
suggested to harbour more zoonotic viruses than any other mammalian order. Infections in …

Reference-quality bat genomes illuminate adaptations to viral tolerance and disease resistance

A Morales, Y Dong, T Brown, K Baid, D Kontopoulos… - 2023 - par.nsf.gov
Bats carry viruses that can cause severe disease in other mammals. Asymptomatic
infections in bats suggest limited tissue-damaging inflammation and immunopathology. To …