Micro total analysis systems. Latest advancements and trends

PS Dittrich, K Tachikawa, A Manz - Analytical chemistry, 2006 - ACS Publications
The area of micro total analysis systems (μTAS), also called “lab on a chip”, miniaturized or
microfluidic analysis systems, is a rapidly develo** field. During the last several years, we …

Nanofluidic concentration devices for biomolecules utilizing ion concentration polarization: theory, fabrication, and applications

SJ Kim, YA Song, J Han - Chemical Society Reviews, 2010 - pubs.rsc.org
Recently, a new type of electrokinetic concentration devices has been developed in a
microfluidic chip format, which allows efficient trap** and concentration of biomolecules by …

Electric field driven pum** in microfluidic device

MR Hossan, D Dutta, N Islam, P Dutta - Electrophoresis, 2018 - Wiley Online Library
Pum** of fluids with precise control is one of the key components in a microfluidic device.
The electric field has been used as one of the most popular and efficient nonmechanical …

Nanofluidic preconcentration device in a straight microchannel using ion concentration polarization

SH Ko, YA Song, SJ Kim, M Kim, J Han, KH Kang - Lab on a Chip, 2012 - pubs.rsc.org
In this paper, we introduce a simple, straight microchannel design for a nanofluidic protein
concentration device. Compared with concentration devices previously developed, the …

Electrophoretic separations on microfluidic chips

D Wu, J Qin, B Lin - Journal of Chromatography A, 2008 - Elsevier
This review presents a brief outline and novel developments of electrophoretic separation in
microfluidic chips. Distinct characteristics of microchip electrophoresis (MCE) are discussed …

Poly (dimethylsiloxane)-based protein preconcentration using a nanogap generated by junction gap breakdown

JH Lee, S Chung, SJ Kim, J Han - Analytical chemistry, 2007 - ACS Publications
Simple and efficient sample concentration tools are the key to the application of proteomics
in a biological system. In this paper, we developed a method to realize a nanofluidic …

Massively parallel concentration device for multiplexed immunoassays

SH Ko, SJ Kim, LF Cheow, LD Li, KH Kang, J Han - Lab on a Chip, 2011 - pubs.rsc.org
A massively parallel nanofluidic concentration device array for multiplexed and high-
throughput biomolecule detection is demonstrated. By optimizing the microchannel …

Microfluidic chip: next-generation platform for systems biology

X Feng, W Du, Q Luo, BF Liu - Analytica Chimica Acta, 2009 - Elsevier
Systems biology advocates the understanding of biology at the systems-level, which
requires massive information of correlations among individual components in complex …

Battery operated preconcentration-assisted lateral flow assay

C Kim, YK Yoo, SI Han, J Lee, D Lee, K Lee… - Lab on a Chip, 2017 - pubs.rsc.org
Paper-based analytical devices (eg lateral flow assays) are highly advantageous as
portable diagnostic systems owing to their low costs and ease of use. Because of their low …

Recent advances in IEF in capillary tubes and microchips

K Shimura - Electrophoresis, 2009 - Wiley Online Library
The methodological advancements in CIEF in tubes and microchips during the period
between 2002 and early 2008 are reviewed as a continuation of previous review by the …