Gut microbiota in colorectal cancer development and therapy

CC Wong, J Yu - Nature Reviews Clinical Oncology, 2023 - nature.com
Colorectal cancer (CRC) is one of the commonest cancers globally. A unique aspect of CRC
is its intimate association with the gut microbiota, which forms an essential part of the tumour …

Colorectal cancer and gut microbiota studies in China

Z Wang, W Dan, N Zhang, J Fang, Y Yang - Gut Microbes, 2023 - Taylor & Francis
Colorectal cancer (CRC) is the third most common malignant tumor worldwide. The
incidence and mortality rates of CRC have been increasing in China, possibly due to …

Volatile markers for cancer in exhaled breath—could they be the signature of the gut microbiota?

MP Bhandari, I Polaka, R Vangravs, L Mezmale… - Molecules, 2023 - mdpi.com
It has been shown that the gut microbiota plays a central role in human health and disease.
A wide range of volatile metabolites present in exhaled breath have been linked with gut …

Cell free supernatants of Bifidobacterium adolescentis and Bifidobacterium longum suppress the tumor growth in colorectal cancer organoid model

MJ Kim, MH Song, YS Ji, JW Park, YK Shin, SC Kim… - Scientific Reports, 2025 - nature.com
The probiotic gut microbiome and its metabolites are pivotal in regulating host metabolism,
inflammation, and immunity. Host genetics, colonization at birth, the host lifestyle, and …

Heart failure-induced microbial dysbiosis contributes to colonic tumour formation in mice

S de Wit, L Geerlings, C Shi, J Dronkers… - Cardiovascular …, 2024 - academic.oup.com
Aims Heart failure (HF) and cancer are the leading causes of death worldwide.
Epidemiological studies revealed that HF patients are prone to develop cancer. Preclinical …

Gut virome profiling identifies an association between temperate phages and colorectal cancer promoted by Helicobacter pylori infection

S Luo, J Ru, MK Mirzaei, J Xue, X Peng, A Ralser… - Gut …, 2023 - Taylor & Francis
Colorectal cancer (CRC) is one of the most commonly diagnosed cancers worldwide. While
a close correlation between chronic Helicobacter pylori infection and CRC has been …

[HTML][HTML] Inhibition of the NF-κB/HIF-1α signaling pathway in colorectal cancer by tyrosol: a gut microbiota-derived metabolite

J Guo, F Meng, R Hu, L Chen, J Chang… - Journal for …, 2024 - pmc.ncbi.nlm.nih.gov
Background The development and progression of colorectal cancer (CRC) are influenced by
the gut environment, much of which is modulated by microbial-derived metabolites. Although …

Commensal Fecal Microbiota Profiles Associated with Initial Stages of Intestinal Mucosa Damage: A Pilot Study

S Ruiz-Saavedra, S Arboleya, AM Nogacka… - Cancers, 2023 - mdpi.com
Simple Summary The high incidence and mortality of colorectal cancer (CRC) have
influenced society to promote research in this field. Dysbiosis of the intestinal microbiota …

[HTML][HTML] Fecal Microbial Dysbiosis Is Associated with Colorectal Cancer Risk in a Korean Population

J Kim, M Gunathilake, HY Yeo, JH Oh… - … : Official Journal of …, 2024 - pmc.ncbi.nlm.nih.gov
Purpose The association between the fecal microbiota and colorectal cancer (CRC) risk has
been suggested in epidemiologic studies. However, data from large-scale population-based …

Exploring the gut microbiome: A potential biomarker for cancer diagnosis, prognosis, and therapy

EJ Han, JS Ahn, YJ Choi, DH Kim, JS Choi… - … et Biophysica Acta (BBA …, 2024 - Elsevier
The gut microbiome, a complex community of trillions of microorganisms in the intestines, is
crucial in maintaining human health. Recent advancements in microbiome research have …