Thioamides, which are fascinating isosteres of amides, have garnered significant attention in
drug discovery and medicinal chemistry programs, spanning peptides and small molecule …

Malaria has been a major parasitic disease in tropical and subtropical regions and is
estimated to kill between one and two million people (mainly children) every year. Novel anti …

A simple and environmentally friendly electrochemical synthesis method is presented for the
selenylation of tetrahydroquinolines with diselenides. By adjusting the reaction conditions …

Our previous study identified 52 antiplasmodial peptaibols isolated from fungi. To
understand their antiplasmodial mechanism of action, we conducted phenotypic assays …

A novel electrochemical method is described for the direct oxidative C–N coupling of
tetrahydroquinolines and azoles, enabling the synthesis of dihydroquinoline derivatives …

Introduction Despite substantial progress in the field, malaria remains a global health issue
and currently available control strategies are not sufficient to achieve eradication. Agents …

The 4-aminoquinoline moiety is widely present in various bioactive compounds and
marketed drugs, while the preparation of this target structure relies heavily on the amination …

Herein we describe synthesis and evaluation of 4-aminoquinoline derivatives as anticancer
agents. By using Friedlander type condensation and cyclization reactions, the new …

A metal‐free, base‐mediated, and atom‐efficient oxidative dehydrogenative coupling of
substituted phenylmethanols (benzyl alcohols) with methyl azaarenes or phenylacetonitriles …

Parasitic diseases remain a significant global health challenge, especially in develo**
countries, contributing to approximately one million deaths annually. Notably, among the …