Background Primaquine is used to eliminate Plasmodium vivax hypnozoites, but its optimal
dosing regimen remains unclear. We undertook a systematic review and individual patient …

Introduction There are positive aspects regarding the prescribing of fixed dose combinations
(FDCs) versus prescribing the medicines separately. However, these have to be balanced …

The prevention and treatment of Plasmodium vivax malaria | PLOS Medicine Skip to main
content Advertisement PLOS Medicine Browse Current Issue Journal Archive Special Issues …

Background Imperfect adherence is a major barrier to effective primaquine radical cure of
Plasmodium vivax. This study investigated the effect of reduced adherence on the risk of P …

Background Plasmodium vivax liver stages (hypnozoites) may cause relapses, prolonging
morbidity, and impeding malaria control and elimination. The World Health Organization …

Abstract Background Since 2015, the Global Technical Strategy (GTS) for Malaria 2016–
2030 has been adopted by the World Health Organization (WHO) as a comprehensive …

The present paper aims to establish different treatments for neglected tropical disease by a
survey on drug conjugations and possible fixed-dose combinations (FDC) used to obtain …

Background Artemisinin-based combination therapy (ACT) is recommended for
uncomplicated Plasmodium vivax malaria in areas of emerging chloroquine resistance. We …

Emerging Plasmodium vivax resistance to chloroquine (CQ) may undermine malaria
elimination efforts in South America. CQ-resistant P. vivax has been found in the major port …

Abstract Background In Colombia, published studies on the treatment of uncomplicated
Plasmodium vivax malaria with chloroquine-primaquine are scarce. The aim of this study …