Inhibition of apoptosis by intracellular protozoan parasites

VT Heussler, P Küenzi, S Rottenberg - International journal for parasitology, 2001 - Elsevier
Protozoan parasites which reside inside a host cell avoid direct destruction by the immune
system of the host. The infected cell, however, still has the capacity to counteract the …

Hijacking of host cellular functions by the Apicomplexa

F Plattner, D Soldati-Favre - Annu. Rev. Microbiol., 2008 - annualreviews.org
Intracellular pathogens such as viruses and bacteria subvert all the major cellular functions
of their hosts. Targeted host processes include protein synthesis, membrane trafficking …

Hijacking of Host Cell IKK Signalosomes by the Transforming Parasite Theileria

VT Heussler, S Rottenberg, R Schwab, P Küenzi… - Science, 2002 - science.org
Parasites have evolved a plethora of mechanisms to ensure their propagation and evade
antagonistic host responses. The intracellular protozoan parasite Theileria is the only …

Toxoplasma gondii triggers Gi-dependent PI 3-kinase signaling required for inhibition of host cell apoptosis

L Kim, EY Denkers - Journal of Cell Science, 2006 - journals.biologists.com
Infection with the intracellular parasite Toxoplasma gondii renders cells resistant to multiple
pro-apoptotic signals, but underlying mechanisms have not been delineated. The …

The strategies of the Theileria parasite: a new twist in host–pathogen interactions

DAE Dobbelaere, P Küenzi - Current opinion in immunology, 2004 - Elsevier
Theileria parasites infect and transform cells of the ruminant immune system. Continuous
proliferation and survival of Theileria-transformed cells involves the well-orchestrated …

Theileria-induced leukocyte transformation

DAE Dobbelaere, S Rottenberg - Current opinion in microbiology, 2003 - Elsevier
The intracellular protozoan parasites Theileria parva and T. annulata transform the cells they
infect, inducing uncontrolled proliferation. This is not a trivial event as, in addition to …

A Bovine Lymphosarcoma Cell Line Infected with Theileria annulata Exhibits an Irreversible Reconfiguration of Host Cell Gene Expression

JH Kinnaird, W Weir, Z Durrani, SS Pillai, M Baird… - Plos one, 2013 - journals.plos.org
Theileria annulata, an intracellular parasite of bovine lymphoid cells, induces substantial
phenotypic alterations to its host cell including continuous proliferation, cytoskeletal changes …

Expression of anti-apoptotic factors in cells parasitized by second-generation schizonts of Eimeria tenella and Eimeria necatrix

E Del Cacho, M Gallego, F López-Bernad, J Quílez… - Veterinary …, 2004 - Elsevier
Intracellular infections by parasites require a functional anti-apoptotic mechanism for
parasite survival within the host cell. The intracellular cycle of Eimeria tenella and Eimeria …

Dysregulation of macrophage signal transduction by Toxoplasma gondii: past progress and recent advances

J Leng, BA Butcher, EY Denkers - Parasite immunology, 2009 - Wiley Online Library
The opportunistic protozoan parasite Toxoplasma gondii is well known as a strong inducer
of cell‐mediated immunity, largely as a result of proinflammatory cytokine induction during in …

The Akt/PKB pathway is constitutively activated in Theileria‐transformed leucocytes, but does not directly control constitutive NF‐κB activation

VT Heussler, P Küenzi, F Fraga… - Cellular …, 2001 - Wiley Online Library
The intracellular protozoan parasites Theileria parva and Theileria annulata transform
leucocytes by interfering with host cell signal transduction pathways. They differ from tumour …