Dysregulation of cancer cell metabolism contributes to abnormal cell growth, the biological
end point of cancer. We review here numerous affected oncogenes and metabolic pathways …

Several signaling pathways and basic metabolites are responsible for the control of
metabolism in both normal and cancer cells. As emerging hallmarks of cancer metabolism …

Stress-induced cleavage of transfer RNAs (tRNAs) into tRNA-derived fragments (tRFs)
occurs across organisms from yeast to humans; yet, its mechanistic underpinnings and …

Metabolic reprogramming toward aerobic glycolysis unavoidably induces methylglyoxal
(MG) formation in cancer cells. MG mediates the glycation of proteins to form advanced …

Breast cancers possess fundamentally altered metabolism that fuels their pathogenicity.
While many metabolic drivers of breast cancers have been identified, the metabolic …

Several studies have identified a specific metabolic program that is associated with the
process of epithelial-mesenchymal transition (EMT). Whereas much is known about the …

tRNA-derived fragments (tRFs) are a new classification of small non-coding RNAs
(sncRNAs) derived from the specific cleavage of precursors and mature tRNAs …

Metastasis is a major obstacle to the efficient and successful treatment of cancer. Initiation of
metastasis requires epithelial‐mesenchymal transition (EMT) that is regulated by several …

As a vital micronutrient, zinc is integral to the structure, function, and signaling networks of
diverse proteins. Dysregulated zinc levels, due to either excess intake or deficiency, are …

Platelet-activating factor (PAF) is a potent phospholipid mediator that was first described by
its ability to cause platelet aggregation and dilation of blood vessels. Now it is also known as …