Human and economic impacts of natural disasters: can we trust the global data?

RL Jones, D Guha-Sapir, S Tubeuf - Scientific data, 2022 - nature.com
Reliable and complete data held in disaster databases are imperative to inform effective
disaster preparedness and mitigation policies. Nonetheless, disaster databases are highly …

Cost and effects of integrated care: a systematic literature review and meta-analysis

S Rocks, D Berntson, A Gil-Salmerón, M Kadu… - The European Journal of …, 2020 - Springer
Background Health and care services are becoming increasingly strained and healthcare
authorities worldwide are investing in integrated care in the hope of delivering higher-quality …

Rehabilitation versus surgical reconstruction for non-acute anterior cruciate ligament injury (ACL SNNAP): a pragmatic randomised controlled trial

DJ Beard, L Davies, JA Cook, J Stokes, J Leal… - The Lancet, 2022 - thelancet.com
Background Anterior cruciate ligament (ACL) rupture is a common debilitating injury that can
cause instability of the knee. We aimed to investigate the best management strategy …

Oral versus intravenous antibiotics for bone and joint infection

HK Li, I Rombach, R Zambellas… - … England Journal of …, 2019 - Mass Medical Soc
Background The management of complex orthopedic infections usually includes a
prolonged course of intravenous antibiotic agents. We investigated whether oral antibiotic …

Laparoscopic versus open resection for colorectal liver metastases: the OSLO-COMET randomized controlled trial

ÅA Fretland, VJ Dagenborg, GMW Bjørnelv… - Annals of …, 2018 - journals.lww.com
Objective: To perform the first randomized controlled trial to compare laparoscopic and open
liver resection. Summary Background Data: Laparoscopic liver resection is increasingly …

Temporary treatment cessation versus continuation of first-line tyrosine kinase inhibitor in patients with advanced clear cell renal cell carcinoma (STAR): An open-label …

JE Brown, KL Royle, W Gregory, C Ralph… - The lancet …, 2023 - thelancet.com
Background Temporary drug treatment cessation might alleviate toxicity without substantially
compromising efficacy in patients with cancer. We aimed to determine if a tyrosine kinase …

[HTML][HTML] Impact of video-assisted thoracoscopic lobectomy versus open lobectomy for lung cancer on recovery assessed using self-reported physical function: VIOLET …

E Lim, RA Harris, HE McKeon… - Health Technology …, 2022 - pmc.ncbi.nlm.nih.gov
BACKGROUND Lung cancer is the leading cause of cancer death. Surgery remains the
main method of managing early-stage disease. Minimal-access video-assisted …

The clinical and cost-effectiveness of total versus partial knee replacement in patients with medial compartment osteoarthritis (TOPKAT): 5-year outcomes of a …

DJ Beard, LJ Davies, JA Cook, G MacLennan, A Price… - The Lancet, 2019 - thelancet.com
Background Late-stage isolated medial knee osteoarthritis can be treated with total knee
replacement (TKR) or partial knee replacement (PKR). There is high variation in treatment …

Management of adults with primary frozen shoulder in secondary care (UK FROST): a multicentre, pragmatic, three-arm, superiority randomised clinical trial

A Rangan, SD Brealey, A Keding, B Corbacho… - The Lancet, 2020 - thelancet.com
Background Manipulation under anaesthesia and arthroscopic capsular release are costly
and invasive treatments for frozen shoulder, but their effectiveness remains uncertain. We …

The evolving landscape of pulmonary arterial hypertension clinical trials

J Weatherald, A Boucly, A Peters, D Montani, K Prasad… - The Lancet, 2022 - thelancet.com
Although it is a rare disease, the number of available therapeutic options for treating
pulmonary arterial hypertension has increased since the late 1990s, with multiple drugs …