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Evaluation and management of the child and adult with Fontan circulation: a scientific statement from the American Heart Association
It has been 50 years since Francis Fontan pioneered the operation that today bears his
name. Initially designed for patients with tricuspid atresia, this procedure is now offered for a …
name. Initially designed for patients with tricuspid atresia, this procedure is now offered for a …
Neurodevelopmental outcomes for individuals with congenital heart disease: updates in neuroprotection, risk-stratification, evaluation, and management: a scientific …
Over the past decade, new research has advanced scientific knowledge of
neurodevelopmental trajectories, factors that increase neurodevelopmental risk, and …
neurodevelopmental trajectories, factors that increase neurodevelopmental risk, and …
Fetal brain volume predicts neurodevelopment in congenital heart disease
Background: Neurodevelopmental impairment is common in children with congenital heart
disease (CHD), but postnatal variables explain only 30% of the variance in outcomes. To …
disease (CHD), but postnatal variables explain only 30% of the variance in outcomes. To …
White matter injury in the preterm infant: pathology and mechanisms
The human preterm brain is particularly susceptible to cerebral white matter injury (WMI) that
disrupts the normal progression of developmental myelination. Advances in the care of …
disrupts the normal progression of developmental myelination. Advances in the care of …
Brain in congenital heart disease across the lifespan: the cumulative burden of injury
A Marelli, SP Miller, BS Marino, AL Jefferson… - Circulation, 2016 - ahajournals.org
The number of patients surviving with congenital heart disease (CHD) has soared over the
last 3 decades. Adults constitute the fastest-growing segment of the CHD population, now …
last 3 decades. Adults constitute the fastest-growing segment of the CHD population, now …
Trends in congenital heart disease: the next decade
Triedman and Newburger Trends in Congenital Heart Disease 2717 validating these
extraordinary procedural and technical innovations has been described and communicated …
extraordinary procedural and technical innovations has been described and communicated …
Neurodevelopmental outcomes in children with congenital heart disease—what can we impact?
Objectives: The objectives of this review are to discuss the scope of neurologic injuries in
newborns with congenital heart disease, the mechanisms of injury, including prenatal, pre …
newborns with congenital heart disease, the mechanisms of injury, including prenatal, pre …
Exploring early human brain development with structural and physiological neuroimaging
Early brain development, from the embryonic period to infancy, is characterized by rapid
structural and functional changes. These changes can be studied using structural and …
structural and functional changes. These changes can be studied using structural and …
Fetal brain development in congenital heart disease
Neurodevelopmental impairments are the most common extracardiac morbidities among
patients with complex congenital heart disease (CHD) across the lifespan. Robust clinical …
patients with complex congenital heart disease (CHD) across the lifespan. Robust clinical …
Neurodevelopmental abnormalities and congenital heart disease: insights into altered brain maturation
In the past 2 decades, it has become evident that individuals born with congenital heart
disease (CHD) are at risk of develo** life-long neurological deficits. Multifactorial risk …
disease (CHD) are at risk of develo** life-long neurological deficits. Multifactorial risk …