CXCR3 in T cell function

JR Groom, AD Luster - Experimental cell research, 2011 - Elsevier
CXCR3 is a chemokine receptor that is highly expressed on effector T cells and plays an
important role in T cell trafficking and function. CXCR3 is rapidly induced on naïve cells …

CXCR3 ligands: redundant, collaborative and antagonistic functions

JR Groom, AD Luster - Immunology and cell biology, 2011 - Wiley Online Library
CXCR3 is a chemokine receptor that is rapidly induced on naïve T cells following activation,
and preferentially remains highly expressed on type‐1 helper (Th1)‐type CD4+ T cells …

Advances in leishmaniasis

HW Murray, JD Berman, CR Davies, NG Saravia - The Lancet, 2005 - thelancet.com
Governed by parasite and host factors and immunoinflammatory responses, the clinical
spectrum of leishmaniasis encompasses subclinical (inapparent), localised (skin lesions) …

The cytokine/chemokine response in Leishmania/HIV infection and co-infection

S Maksoud, J El Hokayem - Heliyon, 2023 - cell.com
HIV infection progressively weakens the immune system by infecting and destroying cells
involved in host defense. Viral infection symptoms are generated and aggravated as …

The severity of visceral leishmaniasis correlates with elevated levels of serum IL-6, IL-27 and sCD14

PL Dos Santos, FA de Oliveira… - PLoS neglected …, 2016 - journals.plos.org
Background Visceral leishmaniasis (VL) is a severe disease caused by infection with
protozoa of the genus Leishmania. Classic VL is characterized by a systemic infection of …

Balance of IL-10 and interferon-γ plasma levels in human visceral leishmaniasis: implications in the pathogenesis

A Caldas, C Favali, D Aquino, V Vinhas… - BMC infectious …, 2005 - Springer
Background Leishmaniasis remains a serious public health problem in several parts of the
develo** world. Effective prophylactic measurements are hampered by imprecise …

Quantification of parasite load in clinical samples of leishmaniasis patients: IL-10 level correlates with parasite load in visceral leishmaniasis

S Verma, R Kumar, GK Katara, LC Singh, NS Negi… - PloS one, 2010 - journals.plos.org
A rapid and accurate method to detect and quantify Leishmania parasite is urgently needed
to facilitate early diagnosis of Leishmaniasis and monitoring of antileishmania therapy. In …

Efficacy of artemisinin in experimental visceral leishmaniasis

R Sen, S Ganguly, P Saha, M Chatterjee - International Journal of …, 2010 - Elsevier
Visceral leishmaniasis (VL), caused by the protozoan Leishmania sp., affects 500000
people annually, with the Indian subcontinent contributing a significant proportion of these …

Immunopathogenesis of non-healing American cutaneous leishmaniasis and progressive visceral leishmaniasis

L Soong, CA Henard, PC Melby - Seminars in immunopathology, 2012 - Springer
The outcomes of Leishmania infection are determined by host immune and nutrition status,
parasite species, and co-infection with other pathogens. While subclinical infection and self …

Immunotherapy and immunochemotherapy in visceral leishmaniasis: promising treatments for this neglected disease

BM Roatt, RDO Aguiar-Soares, W Coura-Vital… - Frontiers in …, 2014 - frontiersin.org
Leishmaniasis has several clinical forms: self-healing or chronic cutaneous leishmaniasis or
post-kala-azar dermal leishmaniasis; mucosal leishmaniasis; visceral leishmaniasis (VL) …