Functionalizing DNA origami to investigate and interact with biological systems

GA Knappe, EC Wamhoff, M Bathe - Nature Reviews Materials, 2023 - nature.com
DNA origami has emerged as a powerful method to generate DNA nanostructures with
dynamic properties and nanoscale control. These nanostructures enable complex …

Functionalizing framework nucleic‐acid‐based nanostructures for biomedical application

T Zhang, T Tian, Y Lin - Advanced Materials, 2022 - Wiley Online Library
Strategies for functionalizing diverse tetrahedral framework nucleic acids (tFNAs) have been
extensively explored since the first successful fabrication of tFNA by Turberfield. One‐pot …

Thermal‐responsive MXene‐DNA hydrogel for near‐infrared light triggered localized photothermal‐chemo synergistic cancer therapy

PP He, X Du, Y Cheng, Q Gao, C Liu, X Wang, Y Wei… - Small, 2022 - Wiley Online Library
Stimuli‐responsive DNA hydrogels are promising candidates for cancer treatment, as they
not only possess biocompatible and biodegradable 3D network structures as highly efficient …

Designer DNA nanostructures for therapeutics

S Jiang, Z Ge, S Mou, H Yan, C Fan - Chem, 2021 - cell.com
The field of structural DNA nanotechnology applies the programmability of Watson-Crick
base pairing to the construction of custom nanostructures that are prescribed by the …

DNA Origami: From Molecular Folding Art to Drug Delivery Technology

Q Jiang, Y Shang, Y **e, B Ding - Advanced Materials, 2024 - Wiley Online Library
DNA molecules that store genetic information in living creatures can be repurposed as
building blocks to construct artificial architectures, ranging from the nanoscale to the …

[HTML][HTML] Aptamer-enabled nanomaterials for therapeutics, drug targeting and imaging

M Liu, L Wang, Y Lo, SCC Shiu, AB Kinghorn… - Cells, 2022 - mdpi.com
A wide variety of nanomaterials have emerged in recent years with advantageous properties
for a plethora of therapeutic and diagnostic applications. Such applications include drug …

Environment‐dependent stability and mechanical properties of DNA origami six‐helix bundles with different crossover spacings

Y **n, P Piskunen, A Suma, C Li, H Ijäs, S Ojasalo… - Small, 2022 - Wiley Online Library
The internal design of DNA nanostructures defines how they behave in different
environmental conditions, such as endonuclease‐rich or low‐Mg2+ solutions. Notably, the …

Engineering inorganic materials with DNA nanostructures

A Heuer-Jungemann, V Linko - ACS Central Science, 2021 - ACS Publications
Nucleic acid nanotechnology lays a foundation for the user-friendly design and synthesis of
DNA frameworks of any desirable shape with extreme accuracy and addressability …

DNA-origami-directed virus capsid polymorphism

I Seitz, S Saarinen, EP Kumpula, D McNeale… - Nature …, 2023 - nature.com
Viral capsids can adopt various geometries, most iconically characterized by icosahedral or
helical symmetries. Importantly, precise control over the size and shape of virus capsids …

Hybrid nanostructures: Versatile systems for biomedical applications

S Mehta, A Suresh, Y Nayak, R Narayan… - Coordination Chemistry …, 2022 - Elsevier
Hybrid nanostructures are nanocomposites constructed from at least two different types of
materials to imbibe the individual advantages while overcoming individual shortcomings …