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Functionalizing DNA origami to investigate and interact with biological systems
DNA origami has emerged as a powerful method to generate DNA nanostructures with
dynamic properties and nanoscale control. These nanostructures enable complex …
dynamic properties and nanoscale control. These nanostructures enable complex …
Functionalizing framework nucleic‐acid‐based nanostructures for biomedical application
T Zhang, T Tian, Y Lin - Advanced Materials, 2022 - Wiley Online Library
Strategies for functionalizing diverse tetrahedral framework nucleic acids (tFNAs) have been
extensively explored since the first successful fabrication of tFNA by Turberfield. One‐pot …
extensively explored since the first successful fabrication of tFNA by Turberfield. One‐pot …
Thermal‐responsive MXene‐DNA hydrogel for near‐infrared light triggered localized photothermal‐chemo synergistic cancer therapy
PP He, X Du, Y Cheng, Q Gao, C Liu, X Wang, Y Wei… - Small, 2022 - Wiley Online Library
Stimuli‐responsive DNA hydrogels are promising candidates for cancer treatment, as they
not only possess biocompatible and biodegradable 3D network structures as highly efficient …
not only possess biocompatible and biodegradable 3D network structures as highly efficient …
DNA origami: from molecular folding art to drug delivery technology
Q Jiang, Y Shang, Y **e, B Ding - Advanced Materials, 2024 - Wiley Online Library
DNA molecules that store genetic information in living creatures can be repurposed as
building blocks to construct artificial architectures, ranging from the nanoscale to the …
building blocks to construct artificial architectures, ranging from the nanoscale to the …
Enhanced postsurgical cancer treatment using methacrylated glycol chitosan hydrogel for sustained DNA/doxorubicin delivery and immunotherapy
Background: Cancer recurrence and metastasis are major contributors to treatment failure
following tumor resection surgery. We developed a novel implantable drug delivery system …
following tumor resection surgery. We developed a novel implantable drug delivery system …
[HTML][HTML] Rhabdomyosarcoma: current therapy, challenges, and future approaches to treatment strategies
Simple Summary Rhabdomyosarcoma (RMS) is a rare pediatric sarcoma affecting skeletal
muscle in children and young adults. It is responsible for 3% of all childhood malignant …
muscle in children and young adults. It is responsible for 3% of all childhood malignant …
Designer DNA nanostructures for therapeutics
The field of structural DNA nanotechnology applies the programmability of Watson-Crick
base pairing to the construction of custom nanostructures that are prescribed by the …
base pairing to the construction of custom nanostructures that are prescribed by the …
DNA Framework‐Enabled 3D Organization of Antiarrhythmic Drugs for Radiofrequency Catheter Ablation
Preorganizing molecular drugs within a microenvironment is crucial for the development of
efficient and controllable therapeutic systems. Here, the use of tetrahedral DNA framework …
efficient and controllable therapeutic systems. Here, the use of tetrahedral DNA framework …
DNA-origami-directed virus capsid polymorphism
I Seitz, S Saarinen, EP Kumpula, D McNeale… - Nature …, 2023 - nature.com
Viral capsids can adopt various geometries, most iconically characterized by icosahedral or
helical symmetries. Importantly, precise control over the size and shape of virus capsids …
helical symmetries. Importantly, precise control over the size and shape of virus capsids …
[HTML][HTML] Aptamer-enabled nanomaterials for therapeutics, drug targeting and imaging
A wide variety of nanomaterials have emerged in recent years with advantageous properties
for a plethora of therapeutic and diagnostic applications. Such applications include drug …
for a plethora of therapeutic and diagnostic applications. Such applications include drug …