Reactive oxygen species (ROS) are a chemically defined group of reactive molecules
derived from molecular oxygen. ROS are involved in a plethora of processes in cells in all …

Increased reactive oxygen species (ROS) production has been detected in various cancers
and has been shown to have several roles, for example, they can activate pro-tumourigenic …

Oxygen-derived free radicals, collectively termed reactive oxygen species (ROS), play
important roles in immunity, cell growth, and cell signaling. In excess, however, ROS are …

NADPH oxidases of the Nox family are important enzymatic sources of reactive oxygen
species (ROS). Numerous homologue-specific mechanisms control the activity of this …

Nicotinamide adenine dinucleotide phosphate (NADPH) oxidases (NOX) are enzymes that
generate superoxide or hydrogen peroxide from molecular oxygen utilizing NADPH as an …

atherosclerosis, hypertension, cardiac hypertrophy and remodeling, angiogenesis and
collateral formation, stroke, and heart failure. In this review, we discuss in detail the …

Reactive oxygen species (ROS) including superoxide anion and hydrogen peroxide (H 2 O
2) are thought to be byproducts of aerobic respiration with damaging effects on DNA …

For a long time, superoxide generation by an NADPH oxidase was considered as an oddity
only found in professional phagocytes. Over the last years, six homologs of the cytochrome …

Reactive oxygen species (ROS) are a chemical class of molecules that have generally been
conceptualized as deleterious entities, albeit ones whose destructive properties could be …

Nox4 is an oddity among members of the Nox family of NADPH oxidases [seven isoenzymes
that generate reactive oxygen species (ROS) from molecular oxygen] in that it is …