Advances in cellular and molecular predatory biology of Bdellovibrio bacteriovorus six decades after discovery

TF Lai, RM Ford, SG Huwiler - Frontiers in Microbiology, 2023 - frontiersin.org
Since its discovery six decades ago, the predatory bacterium Bdellovibrio bacteriovorus has
sparked recent interest as a potential remedy to the antibiotic resistance crisis. Here we give …

Extended chloramination significantly enriched intracellular antibiotic resistance genes in drinking water treatment plants

H Li, H Yu, Y Liang, X Zhang, D Yang, L Wang, D Shi… - Water research, 2023 - Elsevier
Chloramination and chlorination are both strong barriers that prevent the transmission of
potential pathogens to humans through drinking water. However, the comparative effects of …

Conformational restriction shapes the inhibition of a multidrug efflux adaptor protein

B Russell Lewis, MR Uddin, M Moniruzzaman… - Nature …, 2023 - nature.com
Membrane efflux pumps play a major role in bacterial multidrug resistance. The tripartite
multidrug efflux pump system from Escherichia coli, AcrAB-TolC, is a target for inhibition to …

Efflux pumps as potential targets for biofilm inhibition

J Ren, M Wang, W Zhou, Z Liu - Frontiers in Microbiology, 2024 - frontiersin.org
Biofilms account for a great deal of infectious diseases and contribute significantly to
antimicrobial resistance. Efflux pumps confer antimicrobial resistance to microorganisms …

A role for the periplasmic adaptor protein AcrA in vetting substrate access to the RND efflux transporter AcrB

I Alav, VN Bavro, JMA Blair - Scientific Reports, 2022 - nature.com
Tripartite resistance-nodulation-division (RND) efflux pumps, such as AcrAB-TolC of
Salmonella Typhimurium, contribute to antibiotic resistance and comprise an inner …

Interplay between two-component regulatory systems is involved in control of Cupriavidus metallidurans metal resistance genes

C Große, J Scherer, G Schleuder… - Journal of Bacteriology, 2023 - Am Soc Microbiol
Metal resistance of Cupriavidus metallidurans is based on determinants that were acquired
in the past by horizontal gene transfer during evolution. Some of these determinants encode …

Comparison of Phenotype and Genotype Virulence and Antimicrobial Factors of Salmonella Typhimurium Isolated from Human Milk

J Pławińska-Czarnak, K Wódz, M Guzowska… - International Journal of …, 2023 - mdpi.com
Salmonella is a common foodborne infection. Many serovars belonging to Salmonella
enterica subsp. enterica are present in the gut of various animal species. They can cause …

Mg2+-dependent mechanism of environmental versatility in a multidrug efflux pump

BR Lewis, MR Uddin, KM Kuo, LMN Shah, NJ Harris… - Structure, 2025 - cell.com
Tripartite resistance nodulation and cell division multidrug efflux pumps span the periplasm
and are major drivers of multidrug resistance among gram-negative bacteria. Cations, such …

Loss of Mobile Genomic Islands in Metal-Resistant, Hydrogen-Oxidizing Cupriavidus metallidurans

C Große, TA Kohl, S Niemann… - Applied and …, 2022 - Am Soc Microbiol
The genome of the metal-resistant, hydrogen-oxidizing bacterium Cupriavidus metallidurans
strain CH34 contains horizontally acquired plasmids and genomic islands. Metal-resistance …

Competition-cooperation mechanism between Escherichia coli and Staphylococcus aureus based on systems map**

C Li, L Yin, X He, Y **, X Zhu, R Wu - Frontiers in Microbiology, 2023 - frontiersin.org
Introduction Interspecies interactions are a crucial driving force of species evolution. The
genes of each coexisting species play a pivotal role in sha** the structure and function …