The year 2017 marks the twentieth anniversary of terpenoid cyclase structural biology: a trio
of terpenoid cyclase structures reported together in 1997 were the first to set the foundation …

For many decades, Escherichia coli was the main model organism for the study of bacterial
membrane lipids. The results obtained served as a blueprint for membrane lipid …

Covering: through June 2021 Terpenoids are the largest class of natural products
recognised to date. While mostly known to humans as bioactive plant metabolites and part of …

The microorganism-microorganism or microorganism-host interactions are the key strategy
to colonize and establish in a variety of different environments. These interactions involve all …

Lipid research represents a frontier for microbiology, as showcased by hopanoid lipids.
Hopanoids, which resemble sterols and are found in the membranes of diverse bacteria …

The functionality of cellular membranes relies on the molecular order imparted by lipids. In
eukaryotes, sterols such as cholesterol modulate membrane order, yet they are not typically …

Gram‐negative bacteria are intrinsically resistant against cytotoxic substances by means of
their outer membrane and a network of multidrug efflux systems, acting in synergy. Efflux …

Squalene is a natural triterpene and an important intermediate of sterol and hopanoid
biosynthesis in various types of cell from bacteria to human. Synthesis and further …

Background Microbes are main drivers of biogeochemical cycles in oceans and lakes.
Although the genome is a foundation for understanding the metabolism, ecology and …

Terpenoids, or isoprenoids, are a family of compounds with great structural diversity which
are essential for all living organisms. In cyanobacteria, they are synthesized from the …