Skin cancer and new treatment perspectives: A review

MCF Simoes, JJS Sousa, AACC Pais - Cancer letters, 2015 - Elsevier
Skin cancers are by far the most common malignancy of humans, particularly in the white
population. The growing incidence of cutaneous malignancies has heralded the need for …

Targeted intracellular delivery of antibodies: the state of the art

TA Slastnikova, AV Ulasov, AA Rosenkranz… - Frontiers in …, 2018 - frontiersin.org
A dominant area of antibody research is the extension of the use of this mighty experimental
and therapeutic tool for the specific detection of molecules for diagnostics, visualization, and …

Targeted photodynamic therapy via receptor mediated delivery systems

WM Sharman, JE van Lier, CM Allen - Advanced drug delivery reviews, 2004 - Elsevier
Targeted photodynamic therapy (PDT) offers the opportunity of enhancing photodynamic
efficiency by directly targeting diseased cells and tissues. While antibody-conjugates have …

Vascular and cellular targeting for photodynamic therapy

B Chen, BW Pogue, PJ Hoopes… - Critical Reviews™ in …, 2006 - dl.begellhouse.com
Photodynamic therapy (PDT) involves the combination of photosensitizers (PS) with light as
a treatment, and has been an established medical practice for about 10 years. Current …

Molecular targeting of drug delivery systems to cancer

T Minko, SS Dharap, RI Pakunlu… - Current drug targets, 2004 - ingentaconnect.com
This review presents molecular targeting approaches in anticancer drug delivery systems
(DDS) and identifies new developments in these systems. Targeting approaches include …

Membrane trafficking and subcellular drug targeting pathways

A Kumar, A Ahmad, A Vyawahare… - Frontiers in pharmacology, 2020 - frontiersin.org
The movement of micro and macro molecules into and within a cell significantly governs
several of their pharmacokinetic and pharmacodynamic parameters, thus regulating the …

Malignant melanoma and melanocortin 1 receptor

AA Rosenkranz, TA Slastnikova, MO Durymanov… - Biochemistry …, 2013 - Springer
The conventional chemotherapeutic treatment of malignant melanoma still remains poorly
efficient in most cases. Thus the use of specific features of these tumors for development of …

Antitumor Activity of Auger Electron Emitter 111In Delivered by Modular Nanotransporter for Treatment of Bladder Cancer With EGFR Overexpression

AA Rosenkranz, TA Slastnikova… - Frontiers in …, 2018 - frontiersin.org
Gamma-ray emitting 111In, which is extensively used for imaging, is also a source of short-
range Auger electrons (AE). While exhibiting negligible effect outside cells, these AE …

Delivery systems exploiting natural cell transport processes of macromolecules for intracellular targeting of Auger electron emitters

AA Rosenkranz, TA Slastnikova, GP Georgiev… - Nuclear Medicine and …, 2020 - Elsevier
The presence of Auger electrons (AE) among the decay products of a number of
radionuclides makes these radionuclides an attractive means for treating cancer because …

Hybrid compounds: from simple combinations to nanomachines

A Müller-Schiffmann, H Sticht, C Korth - BioDrugs, 2012 - Springer
The combination of two different and independently acting compounds into one covalently
linked hybrid compound can convey synergy from the effects of both independently acting …