S. cerevisiae plays a pivotal role as a model system in understanding the biochemistry and
molecular biology of mammals including humans. A considerable portion of our knowledge …

Caffeine–a methylxanthine analogue of the purine bases adenine and guanine–is by far the
most consumed neuro-stimulant, being the active principle of widely consumed beverages …

Background Polycystic ovary syndrome (PCOS) is a complex reproductive endocrine
disorder. And metabolic syndrome (MS) is an important bridge for PCOS patients to develop …

Bacterial antibiotic persistence is a phenomenon where bacteria are exposed to an
antibiotic and the majority of the population dies while a small subset enters a low metabolic …

Translation is the most error‐prone process in protein synthesis; however, it is important that
accuracy is maintained because erroneous translation has been shown to affect all domains …

Transfer RNA (tRNA) has a long-established role in protein synthesis. The tRNA molecule
serves as an adaptor [1] between the genetic instructions written in nucleic acid sequences …

The sla1+ gene of Schizosachharoymces pombe encodes La protein which promotes
proper processing of precursor-tRNAs. Deletion of sla1 (sla1 Δ) leads to disrupted tRNA …

Interactions between proteins from intracellular pathogens and host proteins in an infected
cell are often mediated by post-translational modifications encoded in the host proteome …

Aminoacyl tRNA synthetases (aaRSs) are critical enzymes in translation, being required to
accurately make functional proteins. aaRSs are responsible for correctly aminoacylating a …

Ageing is a malleable process and outstanding discoveries demonstrate that: 1) a single
point mutation can double the lifespan of model organisms, 2) these long-lived animals are …