Abstract Myeloid leukemia 1 (MCL-1) is an antiapoptotic protein of the BCL-2 family that
prevents apoptosis by binding to the pro-apoptotic BCL-2 proteins. Overexpression of MCL …

A significant obstacle to treating cancer is multidrug resistance (MDR), which is the capacity
of cancerous cells to develop resistance to both traditional and cutting-edge …

Cancer is one of the leading causes of death globally. The development of drug resistance
is the main contributor to cancer-related mortality. Cancer cells exploit multiple mechanisms …

Berberine, an isoquinoline alkaloid from Coptidis Rhizoma, has been characterized as a
potential anticancer drug due to its good anti-tumor effects. However, the molecular …

Nuclear factor erythroid 2 p45-related factor (2Nrf2) is an essential leucine zipper protein
(bZIP) that is primarily located in the cytoplasm under physiological conditions. Nrf2 …

Serum protein as naturally essential biomacromolecules has recently emerged as a
versatile carrier for diagnostic and therapeutic drug delivery for cancer nanomedicine with …

Cancer is still one of the major causes of mortality in both develo** and developed
countries. At present, in spite of intensive interventions, a large number of patients suffer …

In recent years, some natural products isolated from the fungi of the genus Ganoderma have
been found to have anti-tumor, liver protection, anti-inflammatory, immune regulation, anti …

Phycocyanin isolated from marine organisms has the characteristics of high efficiency and
low toxicity, and it can be used as a functional food. It has been reported that phycocyanin …

Introduction: Throughout history, natural products (NPs) have provided a rich source of
compounds that have wide applications in the fields of medicine, health sciences, pharmacy …