ROS generation and antioxidant defense systems in normal and malignant cells

AV Snezhkina, AV Kudryavtseva… - Oxidative medicine …, 2019 - Wiley Online Library
Reactive oxygen species (ROS) are by‐products of normal cell activity. They are produced
in many cellular compartments and play a major role in signaling pathways. Overproduction …

Selenium, selenoproteins and viral infection

OM Guillin, C Vindry, T Ohlmann, L Chavatte - Nutrients, 2019 - mdpi.com
Reactive oxygen species (ROS) are frequently produced during viral infections. Generation
of these ROS can be both beneficial and detrimental for many cellular functions. When …

NADPH oxidases: an overview from structure to innate immunity-associated pathologies

A Panday, MK Sahoo, D Osorio, S Batra - Cellular & molecular …, 2015 - nature.com
Oxygen-derived free radicals, collectively termed reactive oxygen species (ROS), play
important roles in immunity, cell growth, and cell signaling. In excess, however, ROS are …

RNA viruses: ROS‐mediated cell death

ML Reshi, YC Su, JR Hong - International journal of cell …, 2014 - Wiley Online Library
Reactive oxygen species (ROS) are well known for being both beneficial and deleterious.
The main thrust of this review is to investigate the role of ROS in ribonucleic acid (RNA) virus …

[HTML][HTML] Chronic hepatitis C and liver fibrosis

G Sebastiani, K Gkouvatsos… - World journal of …, 2014 - ncbi.nlm.nih.gov
Chronic infection with hepatitis C virus (HCV) is a leading cause of liver-related morbidity
and mortality worldwide and predisposes to liver fibrosis and end-stage liver complications …

Potential role of signal transducer and activator of transcription (STAT) 3 signaling pathway in inflammation, survival, proliferation and invasion of hepatocellular …

A Subramaniam, MK Shanmugam, E Perumal… - … et Biophysica Acta (BBA …, 2013 - Elsevier
Hepatocellular carcinoma (HCC) is one of the most lethal malignancies, and is also the
fourth most common cancer worldwide with around 700,000 new cases each year …

Cellular oxidative stress response controls the antiviral and apoptotic programs in dengue virus-infected dendritic cells

D Olagnier, S Peri, C Steel, N van Montfoort… - PLoS …, 2014 - journals.plos.org
Dengue virus (DENV) is a re-emerging arthropod borne flavivirus that infects more than 300
million people worldwide, leading to 50,000 deaths annually. Because dendritic cells (DC) …

Effect of reactive oxygen species on the endoplasmic reticulum and mitochondria during intracellular pathogen infection of mammalian cells

J Lee, CH Song - Antioxidants, 2021 - mdpi.com
Oxidative stress, particularly reactive oxygen species (ROS), are important for innate
immunity against pathogens. ROS directly attack pathogens, regulate and amplify immune …

Oxidative stress, a trigger of hepatitis C and B virus-induced liver carcinogenesis

AV Ivanov, VT Valuev-Elliston, DA Tyurina… - …, 2016 - pmc.ncbi.nlm.nih.gov
Virally induced liver cancer usually evolves over long periods of time in the context of a
strongly oxidative microenvironment, characterized by chronic liver inflammation and …

Therapeutic modulation of virus‐induced oxidative stress via the Nrf2‐dependent antioxidative pathway

C Lee - Oxidative Medicine and Cellular Longevity, 2018 - Wiley Online Library
Virus‐induced oxidative stress plays a critical role in the viral life cycle as well as the
pathogenesis of viral diseases. In response to reactive oxygen species (ROS) generation by …