The development of RNA-based anti-infectives has gained interest with the successful
application of mRNA-based vaccines. Small RNAs are molecules of RNA of< 200 …

The public's health and the financial sustainability of international societies remain
threatened by bacterial zoonoses, with limited reliable diagnostic and therapeutic options …

Abstract Infection with Salmonella Typhimurium (S. Typhimurium) is a common cause of
food-borne zoonosis leading to acute gastroenteritis in humans and pigs, causing economic …

In the face of global health challenges posed by infectious diseases and the emergence of
drug-resistant pathogens, the exploration of cellular non-coding RNA (ncRNA) networks has …

Epithelial cells (ECs) provide the first line of defense against microbial threats and
environmental challenges. They participate in the host's immune responses via the …

Macrophages remove bacteria from the extracellular milieu via phagocytosis. While most of
the engulfed bacteria are degraded in the antimicrobial environment of the phagolysosome …

The host response to S. Typhimurium infection can be post-transcriptionally regulated by
miRNAs. In this study, we investigated the role of miR-215 using both in vivo porcine …

Background Dysregulation of microRNAs has been frequently implicated in the progression
of human diseases, including glioma. This study aims to explore the interaction between …

Macroautophagy is a ubiquitous homeostasis and health-promoting recycling process of
eukaryotic cells, targeting misfolded proteins, damaged organelles and intracellular …

Abstract Background MicroRNAs (miRNAs) and isomiRs play important roles in
tumorigenesis as essential regulators of gene expression. 5'isomiRs exhibit a shifted seed …