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The changing opioid crisis: development, challenges and opportunities
ND Volkow, C Blanco - Molecular psychiatry, 2021 - nature.com
The current opioid epidemic is one of the most severe public health crisis in US history.
Responding to it has been difficult due to its rapidly changing nature and the severity of its …
Responding to it has been difficult due to its rapidly changing nature and the severity of its …
Neurobiology of addiction: a neurocircuitry analysis
GF Koob, ND Volkow - The lancet psychiatry, 2016 - thelancet.com
Drug addiction represents a dramatic dysregulation of motivational circuits that is caused by
a combination of exaggerated incentive salience and habit formation, reward deficits and …
a combination of exaggerated incentive salience and habit formation, reward deficits and …
Cerebellar contributions to the basal ganglia influence motor coordination, reward processing, and movement vigor
Both the cerebellum and the basal ganglia are known for their roles in motor control and
motivated behavior. These two systems have been classically considered as independent …
motivated behavior. These two systems have been classically considered as independent …
Situational strategies for self-control
Exercising self-control is often difficult, whether declining a drink in order to drive home
safely, passing on the chocolate cake to stay on a diet, or ignoring text messages to finish …
safely, passing on the chocolate cake to stay on a diet, or ignoring text messages to finish …
Prefrontal control and Internet addiction: a theoretical model and review of neuropsychological and neuroimaging findings
M Brand, KS Young, C Laier - Frontiers in human neuroscience, 2014 - frontiersin.org
Most people use the Internet as a functional tool to perform their personal goals in everyday-
life such as making airline or hotel reservations. However, some individuals suffer from a …
life such as making airline or hotel reservations. However, some individuals suffer from a …
Cerebellar networks with the cerebral cortex and basal ganglia
The dominant view of cerebellar function has been that it is exclusively concerned with
motor control and coordination. Recent findings from neuroanatomical, behavioral, and …
motor control and coordination. Recent findings from neuroanatomical, behavioral, and …
Obesity and addiction: neurobiological overlaps
Drug addiction and obesity appear to share several properties. Both can be defined as
disorders in which the saliency of a specific type of reward (food or drug) becomes …
disorders in which the saliency of a specific type of reward (food or drug) becomes …
Factors modulating neural reactivity to drug cues in addiction: a survey of human neuroimaging studies
Human neuroimaging studies suggest that neural cue reactivity is strongly associated with
indices of drug use, including addiction severity and treatment success. However, little is …
indices of drug use, including addiction severity and treatment success. However, little is …
Neural mechanisms of addiction: the role of reward-related learning and memory
Addiction is a state of compulsive drug use; despite treatment and other attempts to control
drug taking, addiction tends to persist. Clinical and laboratory observations have converged …
drug taking, addiction tends to persist. Clinical and laboratory observations have converged …
Shared and unique mechanisms underlying binge eating disorder and addictive disorders
Scientific interest in “food addiction” is growing, but the topic remains controversial. One
critique of “food addiction” is its high degree of phenotypic overlap with binge eating …
critique of “food addiction” is its high degree of phenotypic overlap with binge eating …