Phage family classification under Caudoviricetes: A review of current tools using the latest ICTV classification framework

Y Zhu, J Shang, C Peng, Y Sun - Frontiers in microbiology, 2022 - frontiersin.org
Bacteriophages, which are viruses infecting bacteria, are the most ubiquitous and diverse
entities in the biosphere. There is accumulating evidence revealing their important roles in …

Correlation between the gut microbiome and neurodegenerative diseases: a review of metagenomics evidence

X Liu, Y Liu, J Liu, H Zhang, C Shan… - Neural Regeneration …, 2024 - journals.lww.com
A growing body of evidence suggests that the gut microbiota contributes to the development
of neurodegenerative diseases via the microbiota-gut-brain axis. As a contributing factor …

iPHoP: An integrated machine learning framework to maximize host prediction for metagenome-derived viruses of archaea and bacteria

S Roux, AP Camargo, FH Coutinho, SM Dabdoub… - PLoS …, 2023 - journals.plos.org
The extraordinary diversity of viruses infecting bacteria and archaea is now primarily studied
through metagenomics. While metagenomes enable high-throughput exploration of the viral …

PhaTYP: predicting the lifestyle for bacteriophages using BERT

J Shang, X Tang, Y Sun - Briefings in Bioinformatics, 2023 - academic.oup.com
Bacteriophages (or phages), which infect bacteria, have two distinct lifestyles: virulent and
temperate. Predicting the lifestyle of phages helps decipher their interactions with their …

Large language models improve annotation of prokaryotic viral proteins

ZN Flamholz, SJ Biller, L Kelly - Nature microbiology, 2024 - nature.com
Viral genomes are poorly annotated in metagenomic samples, representing an obstacle to
understanding viral diversity and function. Current annotation approaches rely on alignment …

Hi-C metagenome sequencing reveals soil phage–host interactions

R Wu, MR Davison, WC Nelson, ML Smith… - Nature …, 2023 - nature.com
Bacteriophages are abundant in soils. However, the majority are uncharacterized, and their
hosts are unknown. Here, we apply high-throughput chromosome conformation capture (Hi …

COBRA improves the completeness and contiguity of viral genomes assembled from metagenomes

LX Chen, JF Banfield - Nature Microbiology, 2024 - nature.com
Viruses are often studied using metagenome-assembled sequences, but genome
incompleteness hampers comprehensive and accurate analyses. Contig Overlap Based Re …

Rhizosphere phage communities drive soil suppressiveness to bacterial wilt disease

K Yang, X Wang, R Hou, C Lu, Z Fan, J Li, S Wang… - Microbiome, 2023 - Springer
Background Bacterial viruses, phages, play a key role in nutrient turnover and lysis of
bacteria in terrestrial ecosystems. While phages are abundant in soils, their effects on plant …

Global overview and major challenges of host prediction methods for uncultivated phages

C Coclet, S Roux - Current opinion in virology, 2021 - Elsevier
Highlights•Global phage diversity is now primarily explored through cultivation-independent
metagenomics.•Metagenome-derived phages are typically linked to their host (s) via in silico …

[HTML][HTML] Airborne antibiotic resistome and microbiome in pharmaceutical factories

H Bai, LY He, FZ Gao, KS Yao, M Zhang, LK Qiao… - Environment …, 2024 - Elsevier
Antimicrobial resistance is considered to be one of the biggest public health problems, and
airborne transmission is an important but under-appreciated pathway for the spread of …