The miR‐181 family: Wide‐ranging pathophysiological effects on cell fate and function

A Bell‐Hensley, S Das… - Journal of cellular …, 2023 - Wiley Online Library
MicroRNAs (miRNAs) are epigenetic regulators that can target and inhibit translation of
multiple mRNAs within a given cell type. As such, a number of different pathways and …

Anti-inflammatory, anti-fibrotic and pro-cardiomyogenic effects of genetically engineered extracellular vesicles enriched in miR-1 and miR-199a on human cardiac …

K Kmiotek-Wasylewska, S Bobis-Wozowicz… - Stem Cell Reviews and …, 2023 - Springer
Rationale Emerging evidence indicates that stem cell (SC)-derived extracellular vesicles
(EVs) carrying bioactive miRNAs are able to repair damaged or infarcted myocardium and …

Genomic loci mispositioning in Tmem120a knockout mice yields latent lipodystrophy

R Czapiewski, DG Batrakou, JI de Las Heras… - Nature …, 2022 - nature.com
Little is known about how the observed fat-specific pattern of 3D-spatial genome
organisation is established. Here we report that adipocyte-specific knockout of the gene …

NORHA, a novel follicular atresia-related lncRNA, promotes porcine granulosa cell apoptosis via the miR-183-96-182 cluster and FoxO1 axis

W Yao, Z Pan, X Du, J Zhang, H Liu, Q Li - Journal of Animal Science and …, 2021 - Springer
Background Follicular atresia has been shown to be strongly associated with a low follicle
utilization rate and female infertility, which are regulated by many factors such as microRNAs …

Vitisin A-13-O-β-D-glucoside and Vitisin A from Iris lactea inhibit lipogenesis and promote lipolysis via the PKA/HSL pathway during adipogenic transdifferentiation of …

F Tie, N Hu, Q Dong, H Wang - European journal of pharmacology, 2023 - Elsevier
Oligostilbenes are a group of natural products derived from the polymerization of stilbene
monomers. Despite the demonstration of their activities in regulating lipid metabolism, the …

The human novel gene LNC-HC inhibits hepatocellular carcinoma cell proliferation by sequestering hsa-miR-183-5p

X Lan, N Wu, L Wu, K Qu, EK Osoro, D Guan… - … Therapy-Nucleic Acids, 2020 - cell.com
Hepatocellular carcinoma (HCC) is the most commonly diagnosed cancer and the leading
cause of cancer mortality. Several lines of evidence have demonstrated the aberrant …

MicroRNA expression profiles in autism spectrum disorder: role for miR-181 in immunomodulation

RE Frye, S Rose, S McCullough, SC Bennuri… - Journal of Personalized …, 2021 - mdpi.com
Background: MicroRNAs (miRNAs) are important regulators of molecular pathways in
psychiatric disease. Here, we examine differential miRNAs expression in lymphoblastoid …

MicroRNAs mediated regulation of glutathione peroxidase 7 expression and its changes during adipogenesis

B Hanousková, G Vávrová, M Ambrož, I Boušová… - … et Biophysica Acta (BBA …, 2021 - Elsevier
Abstract Glutathione peroxidase 7 (GPx7) acts as an intracellular stress sensor/transmitter
and plays an important role in adipocyte differentiation and the prevention of obesity related …

Chromatin accessibility is associated with the changed expression of miRNAs that target members of the Hippo pathway during myoblast differentiation

H Zhou, Y **ang, M Hu, Y Xu, Y Hou, X Qi, L Fu… - Cell death & …, 2020 - nature.com
Abstract miRNAs reportedly participate in various biological processes, such as skeletal
muscle proliferation and differentiation. However, the regulation of differentially expressed …

Time-series clustering of lncRNA-mRNA expression during the adipogenic transdifferentiation of porcine skeletal muscle satellite cells

X Qiu, G Gao, L Du, J Wang, Q Wang, F Yang… - Current Issues in …, 2022 - mdpi.com
Skeletal muscle satellite cells (SMSCs), which are multifunctional muscle-derived stem cells,
can differentiate into adipocytes. Long-chain non-coding RNA (lncRNA) has diverse …