Chronic stressful life events are risk factors for develo** major depression, the
pathophysiology of which is strongly linked to impairments in serotonin (5-HT) …

The epidermal growth factor receptor (EGFR) is the prototypical member of a family of
membrane-associated intrinsic tyrosine kinase receptors, the ErbB family. EGFR is activated …

Abstract Neuregulin-1 (Nrg-1) is a member of the Neuregulin family of growth factors with
essential roles in the develo** and adult nervous system. Six different types of Nrg-1 (Nrg …

Chrysin is a natural flavonoid which is found in bee propolis, honey and various plants, and
neuroprotective effect of chrysin in mice was previously demonstrated by our group …

Neurodegenerative diseases, including Alzheimer's disease (AD), Parkinson's disease (PD)
and amyotrophic lateral sclerosis (ALS), are typically characterized by progressive neuronal …

Objectives To systematically review findings of GWAS in schizophrenia (SZ) and in bipolar
disorder (BD); and to interpret findings, with a focus on identifying independent replications …

Objective Parkinson's disease (PD) may be caused by the interaction of a number of factors,
including genetics, toxins, oxidative stress, mitochondrial abnormalities, and aging. Studies …

Epigenetics is the study of heritable changes in gene expression that occur without
alterations to the DNA sequence, linking the genome to its surroundings. The accumulation …

Ligands for ErbB1-4 receptor tyrosine kinases, such as epidermal growth factor (EGF) and
neuregulins, regulate brain development and function. Thus, abnormalities in their signaling …

The ErbB network is dysregulated in many solid tumors. To exploit this, we have developed
a chimeric Ag receptor (CAR) named T1E28z that targets several pathogenetically relevant …