The regulation of brain temperature is largely dependent on the metabolic activity of brain
tissue and remains complex. In intensive care clinical practice, the continuous monitoring of …

The earliest recorded application of therapeutic hypothermia in medicine spans about 5000
years; however, its use has become widespread since 2002, following the demonstration of …

Heat transfer in a biological system is a complex process and its analysis is difficult.
Heterogeneous vascular architecture, blood flow in the complex network of arteries and …

Objective: Representatives of five international critical care societies convened topic
specialists and a nonexpert jury to review, assess, and report on studies of targeted …

Examples of clinical applications of therapeutic hypothermia in modern clinical medicine
include traumatic cardiac arrest, ischaemic stroke and, more recently, acute perinatal …

Therapeutic hypothermia (TH) is nowadays one of the most important methods of
neuroprotection. The events that occur after an episode of ischemia are multiple and …

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Especially written for qualified nurses working in intensive care units, this comprehensive
text has been developed to be as accessible as possible. This fourth edition has been …

Aims of the study We aimed to determine the benefit of an expanded use of TH. We also
described the impact of a targeted temperature management on outcomes at discharge …

Abstract Mild hypothermia, 32–35° C, is very potent at reducing myocardial infarct size in
rabbits, dogs, sheep, pigs, and rats. The benefit is directly related to reduction in …