Epigenetic regulation of mitochondrial DNA (mtDNA) is an emerging and fast-develo**
field of research. Compared to regulation of nucler DNA, mechanisms of mtDNA epigenetic …

Reprogramming of cellular energy metabolism is widely accepted to be a cancer hallmark.
The deviant energetic metabolism of cancer cells-known as the Warburg effect-consists in …

The therapeutic potential of the tocotrienol group stems from its nutraceutical properties as a
dietary supplement. It is largely considered to be safe when consumed at low doses for …

Breast cancer is the most ubiquitous type of neoplasms among women worldwide.
Molecular aberrations associated with breast development and progressions have been …

The disappointing results from large clinical studies of α‐tocopherol (αT), the major form of
vitamin E in tissues, for prevention of chronic diseases including cancer have cast doubt on …

Vitamin E is composed of two groups of compounds: α‐, β‐, γ‐, and δ‐tocopherols (TPs),
and the corresponding unsaturated tocotrienols (TTs). TTs are found in natural sources such …

We present the first comprehensive and systematic review on the structurally diverse toco-
chromanols and-chromenols found in photosynthetic organisms, including marine …

Studies on tocotrienols have progressively revealed the benefits of these vitamin E isoforms
on human health. Beta-tocotrienol (beta-T3) is known to be less available in nature …

γ-Tocotrienol, a member of the vitamin E family of compounds, displays potent
antiproliferative and cytotoxic effects in a variety of cancer cell types at treatment doses that …

A large percentage of human breast cancers are characterized by excessive or aberrant
HER2 activity. Lipid rafts are specialized microdomains within the plasma membrane that …