Osteoarthritis is the most common joint disorder with increasing prevalence due to aging of
the population. Its multi-factorial etiology includes oxidative stress and the overproduction of …

Osteoarthritis (OA) is the most common joint disorder and affects approximately half of the
aged population. Current treatments for OA are largely palliative until the articular cartilage …

Temporomandibular joint (TMJ) osteoarthritis is a common chronic degenerative disease of
the TMJ. In order to explore its aetiology and pathological mechanism, many animal models …

Reactive oxygen species (ROS), acting as essential mediators in biological system, play
important roles in the physiologic and pathologic processes, including cellular signal …

Objective Mitochondrial dysfunction, oxidative stress and chondrocyte death are important
contributors to the development and pathogenesis of osteoarthritis (OA). In this study, we …

Osteoarthritis (OA) is one of the most common musculoskeletal disorders worldwide.
Oxidative stress initiated by excessive free radicals such as reactive oxygen species (ROS) …

Osteoarthritis (OA) is one of the most painful and widespread chronic degenerative joint
diseases and is characterized by destructed articular cartilage and inflamed joints …

Osteoarthritis (OA) is a multifactorial chronic disease primarily characterized by the
degeneration of articular cartilage. Currently, there is a lack of effective treatments for OA …

Abstract Interleukin 18 (IL-18) promotes inflammation and apoptosis in chondrocytes,
thereby contributing to the development and progression of osteoarthritis (OA). Here, we …

Osteoarthritis (OA) is a chronic degenerative disease that significantly impacts the quality of
life of the elderly population. Recently, the pathogenesis of OA has been reported to involve …