Toxoplasma gondii is a parasite that infects a wide range of animals and causes zoonotic
infections in humans. Although it normally only results in mild illness in healthy individuals …

Glutamate is the primary excitatory neurotransmitter in the central nervous system (CNS)
which initiates rapid signal transmission in the synapse before its re-uptake into the …

Schizophrenia has been an evolutionary paradox: it has high heritability, but it is associated
with decreased reproductive success. The causal genetic variants underlying schizophrenia …

Inflammation is emerging as a critical mechanism underlying neurological disorders of
various etiologies, yet its role in altering brain function as a consequence of neuroinfectious …

Toxoplasma gondii (T. gondii) is a prevalent protozoan parasite of medical and veterinary
significance. It is the etiologic agent of toxoplasmosis, a neglected disease in which …

Toxoplasma gondii is a widespread parasitic pathogen that infects over one third of the
global human population. The parasite invades and chronically persists in the central …

Toxoplasma gondii is one of the world's most successful parasites, in part because of its
ability to infect and persist in most warm-blooded animals. A unique characteristic of T …

Toxoplasma gondii is an exceptionally successful parasite that infects a very broad host
range, including humans, across the globe. The outcome of infection differs remarkably …

One third of humans are infected lifelong with the brain-dwelling, protozoan parasite,
Toxoplasma gondii. Approximately fifteen million of these have congenital toxoplasmosis …

Activation of extrasynaptic N-methyl-d-aspartate (NMDA) receptors causes
neurodegeneration and cell death. The disease mechanism involves a pathological triad …