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m6A modification: recent advances, anticancer targeted drug discovery and beyond
LJ Deng, WQ Deng, SR Fan, MF Chen, M Qi, WY Lyu… - Molecular cancer, 2022 - Springer
Abstract Abnormal N6-methyladenosine (m6A) modification is closely associated with the
occurrence, development, progression and prognosis of cancer, and aberrant m6A …
occurrence, development, progression and prognosis of cancer, and aberrant m6A …
Review on natural products databases: where to find data in 2020
Natural products (NPs) have been the centre of attention of the scientific community in the
last decencies and the interest around them continues to grow incessantly. As a …
last decencies and the interest around them continues to grow incessantly. As a …
IMPPAT 2.0: an enhanced and expanded phytochemical atlas of Indian medicinal plants
Compilation, curation, digitization, and exploration of the phytochemical space of Indian
medicinal plants can expedite ongoing efforts toward natural product and traditional …
medicinal plants can expedite ongoing efforts toward natural product and traditional …
A drug-likeness toolbox facilitates ADMET study in drug discovery
CY Jia, JY Li, GF Hao, GF Yang - Drug discovery today, 2020 - Elsevier
Highlights•Online resources facilitate in silico drug-likeness study.•Databases gathering
high quality and up to date data are essential for drug-likeness evaluation.•Web servers for …
high quality and up to date data are essential for drug-likeness evaluation.•Web servers for …
Molecular docking study of potential phytochemicals and their effects on the complex of SARS-CoV2 spike protein and human ACE2
Abstract Angiotensin converting enzyme 2 (ACE2)(EC: 3.4. 17.23) is a transmembrane
protein which is considered as a receptor for spike protein binding of novel coronavirus …
protein which is considered as a receptor for spike protein binding of novel coronavirus …
In silico identification of potential inhibitors from Cinnamon against main protease and spike glycoprotein of SARS CoV-2
Cinnamon has been utilized to remedy a lot of afflictions of humans. Literary works illustrate
that it possesses numerous biological activities. Our research study is intended to recognize …
that it possesses numerous biological activities. Our research study is intended to recognize …
Open access in silico tools to predict the ADMET profiling of drug candidates
S Kar, J Leszczynski - Expert opinion on drug discovery, 2020 - Taylor & Francis
Introduction We are in an era of bioinformatics and cheminformatics where we can predict
data in the fields of medicine, the environment, engineering and public health. Approaches …
data in the fields of medicine, the environment, engineering and public health. Approaches …
A computational prediction of SARS-CoV-2 structural protein inhibitors from Azadirachta indica (Neem)
S Borkotoky, M Banerjee - Journal of Biomolecular Structure and …, 2021 - Taylor & Francis
The rapid global spread of the Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-
CoV-2) has created an unprecedented healthcare crisis. The treatment for the severe …
CoV-2) has created an unprecedented healthcare crisis. The treatment for the severe …
Phytochemicals as potential anticancer drugs: time to ponder nature's bounty
MA Ashraf - BioMed research international, 2020 - Wiley Online Library
Medicinal plants have been used from the beginning of human civilization, which is mostly
evident from the ancient script and traditional herbal medicine recipe. Despite the historically …
evident from the ancient script and traditional herbal medicine recipe. Despite the historically …
Advanced network pharmacology study reveals multi-pathway and multi-gene regulatory molecular mechanism of Bacopa monnieri in liver cancer based on data …
Liver cancer is a malignant tumor that grows on the surface or inside the liver. The leading
cause is a viral infection with hepatitis B or C virus. Natural products and their structural …
cause is a viral infection with hepatitis B or C virus. Natural products and their structural …