Understanding the genetic basis of variation in meiotic recombination: past, present, and future
SE Johnston - Molecular Biology and Evolution, 2024 - academic.oup.com
Meiotic recombination is a fundamental feature of sexually reproducing species. It is often
required for proper chromosome segregation and plays important role in adaptation and the …
required for proper chromosome segregation and plays important role in adaptation and the …
Detecting positive selection in the genome
Population geneticists have long sought to understand the contribution of natural selection
to molecular evolution. A variety of approaches have been proposed that use population …
to molecular evolution. A variety of approaches have been proposed that use population …
Conservation genetics as a management tool: The five best-supported paradigms to assist the management of threatened species
About 50 y ago, Crow and Kimura [An Introduction to Population Genetics Theory (1970)]
and Ohta and Kimura [Genet. Res. 22, 201–204 (1973)] laid the foundations of conservation …
and Ohta and Kimura [Genet. Res. 22, 201–204 (1973)] laid the foundations of conservation …
Inference of the distribution of selection coefficients for new nonsynonymous mutations using large samples
The distribution of fitness effects (DFE) has considerable importance in population genetics.
To date, estimates of the DFE come from studies using a small number of individuals. Thus …
To date, estimates of the DFE come from studies using a small number of individuals. Thus …
Molecular population genetics
Molecular population genetics aims to explain genetic variation and molecular evolution
from population genetics principles. The field was born 50 years ago with the first measures …
from population genetics principles. The field was born 50 years ago with the first measures …
Inference of distribution of fitness effects and proportion of adaptive substitutions from polymorphism data
The distribution of fitness effects (DFE) encompasses the fraction of deleterious, neutral, and
beneficial mutations. It conditions the evolutionary trajectory of populations, as well as the …
beneficial mutations. It conditions the evolutionary trajectory of populations, as well as the …
Variation in recombination rate: adaptive or not?
Rates of meiotic recombination are widely variable both within and among species.
However, the functional significance of this variation remains largely unknown. Is the …
However, the functional significance of this variation remains largely unknown. Is the …
The rate of adaptive evolution in animal mitochondria
We have investigated whether there is adaptive evolution in mitochondrial DNA, using an
extensive data set containing over 500 animal species from a wide range of taxonomic …
extensive data set containing over 500 animal species from a wide range of taxonomic …
Diversity and determinants of meiotic recombination landscapes
Despite the universal importance of meiotic recombination for generating genetic diversity,
numbers and distribution of recombination events along chromosomes vary among species …
numbers and distribution of recombination events along chromosomes vary among species …
Selective interference and the evolution of sex
SP Otto - Journal of Heredity, 2021 - academic.oup.com
Selection acts upon genes linked together on chromosomes. This physical connection
reduces the efficiency by which selection can act because, in the absence of sex, alleles …
reduces the efficiency by which selection can act because, in the absence of sex, alleles …