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Major depressive disorder
Major depressive disorder (MDD) is characterized by persistent depressed mood, loss of
interest or pleasure in previously enjoyable activities, recurrent thoughts of death, and …
interest or pleasure in previously enjoyable activities, recurrent thoughts of death, and …
Major depressive disorder: hypothesis, mechanism, prevention and treatment
L Cui, S Li, S Wang, X Wu, Y Liu, W Yu… - Signal transduction and …, 2024 - nature.com
Worldwide, the incidence of major depressive disorder (MDD) is increasing annually,
resulting in greater economic and social burdens. Moreover, the pathological mechanisms …
resulting in greater economic and social burdens. Moreover, the pathological mechanisms …
Neuroinflammation mechanisms of neuromodulation therapies for anxiety and depression
B Guo, M Zhang, W Hao, Y Wang, T Zhang… - Translational …, 2023 - nature.com
Mood disorders are associated with elevated inflammation, and the reduction of symptoms
after multiple treatments is often accompanied by pro-inflammation restoration. A variety of …
after multiple treatments is often accompanied by pro-inflammation restoration. A variety of …
Frontostriatal salience network expansion in individuals in depression
Decades of neuroimaging studies have shown modest differences in brain structure and
connectivity in depression, hindering mechanistic insights or the identification of risk factors …
connectivity in depression, hindering mechanistic insights or the identification of risk factors …
Prefrontal cortex and depression
The prefrontal cortex (PFC) has emerged as one of the regions most consistently impaired in
major depressive disorder (MDD). Although functional and structural PFC abnormalities …
major depressive disorder (MDD). Although functional and structural PFC abnormalities …
Perspective of artificial intelligence in healthcare data management: A journey towards precision medicine
Mounting evidence has highlighted the implementation of big data handling and
management in the healthcare industry to improve the clinical services. Various private and …
management in the healthcare industry to improve the clinical services. Various private and …
Comorbidity between major depressive disorder and physical diseases: a comprehensive review of epidemiology, mechanisms and management
M Berk, O Köhler‐Forsberg, M Turner… - World …, 2023 - Wiley Online Library
Populations with common physical diseases–such as cardiovascular diseases, cancer and
neurodegenerative disorders–experience substantially higher rates of major depressive …
neurodegenerative disorders–experience substantially higher rates of major depressive …
Deep learning models reveal replicable, generalizable, and behaviorally relevant sex differences in human functional brain organization
Sex plays a crucial role in human brain development, aging, and the manifestation of
psychiatric and neurological disorders. However, our understanding of sex differences in …
psychiatric and neurological disorders. However, our understanding of sex differences in …
Resting-state fMRI functional connectivity and mindfulness in clinical and non-clinical contexts: A review and synthesis
This review synthesizes relations between mindfulness and resting-state fMRI functional
connectivity of brain networks. Mindfulness is characterized by present-moment awareness …
connectivity of brain networks. Mindfulness is characterized by present-moment awareness …
[HTML][HTML] Inflammation-related functional and structural dysconnectivity as a pathway to psychopathology
Findings from numerous laboratories and across neuroimaging modalities have consistently
shown that exogenous administration of cytokines or inflammatory stimuli that induce …
shown that exogenous administration of cytokines or inflammatory stimuli that induce …