Applications of artificial intelligence and machine learning in dynamic pathway engineering

C Merzbacher, DA Oyarzún - Biochemical Society Transactions, 2023 - portlandpress.com
Dynamic pathway engineering aims to build metabolic production systems embedded with
intracellular control mechanisms for improved performance. These control systems enable …

Towards parsimonious generative modeling of RNA families

F Calvanese, CN Lambert, P Nghe… - Nucleic Acids …, 2024 - academic.oup.com
Generative probabilistic models emerge as a new paradigm in data-driven, evolution-
informed design of biomolecular sequences. This paper introduces a novel approach, called …

Fast and functional structured data generators rooted in out-of-equilibrium physics

A Carbone, A Decelle, L Rosset… - IEEE Transactions on …, 2024 - ieeexplore.ieee.org
In this study, we address the challenge of using energy-based models to produce high-
quality, label-specific data in complex structured datasets, such as population genetics, RNA …

[HTML][HTML] Deterministic Versus Nondeterministic Optimization Algorithms for the Restricted Boltzmann Machine

GL Zeng - Journal of computational and cognitive engineering, 2024 - pmc.ncbi.nlm.nih.gov
A restricted Boltzmann machine is a fully connected shallow neural network. It can be used
to solve many challenging optimization problems. The Boltzmann machines are usually …