[HTML][HTML] Neurodegenerative proteinopathies induced by environmental pollutants: Heat shock proteins and proteasome as promising therapeutic tools

P Moyano, E Sola, MV Naval, L Guerra-Menéndez… - Pharmaceutics, 2023 - mdpi.com
Environmental pollutants'(EPs) amount and diversity have increased in recent years due to
anthropogenic activity. Several neurodegenerative diseases (NDs) are theorized to be …

Novel drugs affecting diabetic peripheral neuropathy

DO Saleh, AA Sedik - Iranian Journal of Basic Medical …, 2024 - pmc.ncbi.nlm.nih.gov
Diabetic peripheral neuropathy (DPN) poses a significant threat, affecting half of the global
diabetic population and leading to severe complications, including pain, impaired mobility …

Protective effect of magnetic water against AlCl3-induced hepatotoxicity in rats

SA El-Shazly, A Alhejely, HK Alghibiwi… - Scientific Reports, 2024 - nature.com
This study aimed to examine whether or not aluminum chloride (AlCl3)-induced
hepatotoxicity might be mitigated using magnetic water (MW) in rats. This study involved 28 …

Hepatoprotective effects of the xanthine oxidase inhibitor Febuxostat against thioacetamide-induced liver injury in rats: The role of the Nrf2/HO-1 and TLR4/NF-κB …

RS Abdelrahman, ME Abdelmageed - Food and Chemical Toxicology, 2024 - Elsevier
Experimental models of liver injury have been established utilizing thioacetamide (TAA), a
classic liver toxic chemical that causes organ damage via oxidative stress and inflammatory …

Reno-protective effect of fenofibrate and febuxostat against vancomycin-induced acute renal injury in rats: Targeting PPARγ/NF-κB/COX-II and AMPK/Nrf2/HO-1 …

EAM El-Shoura, SMZ Sharkawi… - …, 2024 - Taylor & Francis
Background Vancomycin (VCM) is used clinically to treat serious infections caused by multi-
resistant Gram-positive bacteria, although its use is severely constrained by nephrotoxicity …

Ovario- protective effect of Moringa oleifera leaf extract against cyclophosphamide-induced oxidative ovarian damage and reproductive dysfunction in female rats

SS Soliman, AA Suliman, K Fathy, AA Sedik - Scientific Reports, 2025 - nature.com
It is crucial to develop new tactics to prevent ovarian tissue damage in women whose
reproductive toxicity is caused by chemotherapy. The present investigation was performed to …

Chemical characterization, in vivo anti-oxidant, anti-inflammatory and anti-apoptotic properties of Peperomia pellucida in modulating vascular tone in Swiss mice …

JN Asiwe, GD Yovwin, VO Igben, B Abe… - Pharmacological …, 2024 - Elsevier
Background Regulation of balance between vasoconstriction and vasodilation has become
a therapeutic target to vascular complications. However, Aluminium chloride, a naturally …

Neurodegenerative Proteinopathies Induced by Environmental Pollutants: Heat Shock Proteins and Proteasome as Promising Therapeutic Tools

PV Moyano-Cires Ivanoff, E Sola Vendrell… - 2023 - docta.ucm.es
Environmental pollutants'(EPs) amount and diversity have increased in recent years due to
anthropogenic activity. Several neurodegenerative diseases (NDs) are theorized to be …