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Glycoconjugates: synthesis, functional studies, and therapeutic developments
Glycoconjugates are major constituents of mammalian cells that are formed via covalent
conjugation of carbohydrates to other biomolecules like proteins and lipids and often …
conjugation of carbohydrates to other biomolecules like proteins and lipids and often …
Developments and recent advancements in the field of endogenous amino acid selective bond forming reactions for bioconjugation
O Koniev, A Wagner - Chemical Society Reviews, 2015 - pubs.rsc.org
Bioconjugation methodologies have proven to play a central enabling role in the recent
development of biotherapeutics and chemical biology approaches. Recent endeavours in …
development of biotherapeutics and chemical biology approaches. Recent endeavours in …
Rapid and efficient protein synthesis through expansion of the native chemical ligation concept
The growing interest in proteins, both in fundamental research and in drug discovery, has
fuelled demand for efficient synthetic methods to access these biomolecules. Although solid …
fuelled demand for efficient synthetic methods to access these biomolecules. Although solid …
Peptide coupling reagents, more than a letter soup
In recent years, peptide-coupling reactions have significantly advanced in parallel with the
development of new peptidecoupling reagents, which have been covered in a number of …
development of new peptidecoupling reagents, which have been covered in a number of …
“Click” reactions: a versatile toolbox for the synthesis of peptide-conjugates
W Tang, ML Becker - Chemical Society Reviews, 2014 - pubs.rsc.org
Peptides that comprise the functional subunits of proteins have been conjugated to versatile
materials (biomolecules, polymers, surfaces and nanoparticles) in an effort to modulate cell …
materials (biomolecules, polymers, surfaces and nanoparticles) in an effort to modulate cell …
Nanopore analytics: sensing of single molecules
In nanopore analytics, individual molecules pass through a single nanopore giving rise to
detectable temporary blockades in ionic pore current. Reflecting its simplicity, nanopore …
detectable temporary blockades in ionic pore current. Reflecting its simplicity, nanopore …
Total chemical synthesis of proteins
SBH Kent - Chemical Society Reviews, 2009 - pubs.rsc.org
This tutorial review outlines the modern ligation methods that enable the efficient total
chemical synthesis of enzymes and other protein molecules. Key to this success is the …
chemical synthesis of enzymes and other protein molecules. Key to this success is the …
Chemical protein synthesis: advances, challenges, and outlooks
Contemporary chemical protein synthesis has been dramatically advanced over the past few
decades, which has enabled chemists to reach the landscape of synthetic …
decades, which has enabled chemists to reach the landscape of synthetic …
Glycoprotein synthesis: an update
DP Gamblin, EM Scanlan, BG Davis - Chemical reviews, 2009 - ACS Publications
1.1 Aims This review updates our original review on the synthesis of glycoproteins.(1) Its
aims, therefore, are 2-fold: to highlight, first, key developments since 2002 and, second …
aims, therefore, are 2-fold: to highlight, first, key developments since 2002 and, second …
Antifungal plant defensins: mechanisms of action and production
K Vriens, BPA Cammue, K Thevissen - Molecules, 2014 - mdpi.com
Plant defensins are small, cysteine-rich peptides that possess biological activity towards a
broad range of organisms. Their activity is primarily directed against fungi, but bactericidal …
broad range of organisms. Their activity is primarily directed against fungi, but bactericidal …