Extracellular vesicles in coronary artery disease
CM Boulanger, X Loyer, PE Rautou… - Nature reviews …, 2017 - nature.com
Membrane vesicles released in the extracellular space are composed of a lipid bilayer
enclosing soluble cytosolic material and nuclear components. Extracellular vesicles include …
enclosing soluble cytosolic material and nuclear components. Extracellular vesicles include …
Platelet activation and prothrombotic mediators at the nexus of inflammation and atherosclerosis: Potential role of antiplatelet agents
Platelets are central to inflammation-related manifestations of cardiovascular diseases
(CVD) such as atherosclerosis. Platelet-activating factor (PAF), thrombin, thromboxane A 2 …
(CVD) such as atherosclerosis. Platelet-activating factor (PAF), thrombin, thromboxane A 2 …
Detrimental and protective action of microglial extracellular vesicles on myelin lesions: astrocyte involvement in remyelination failure
M Lombardi, R Parolisi, F Scaroni, E Bonfanti… - Acta …, 2019 - Springer
Microglia are highly plastic immune cells which exist in a continuum of activation states. By
sha** the function of oligodendrocyte precursor cells (OPCs), the brain cells which …
sha** the function of oligodendrocyte precursor cells (OPCs), the brain cells which …
Circulating exosomes suppress the induction of regulatory T cells via let-7i in multiple sclerosis
Multiple sclerosis (MS) is a T cell-mediated autoimmune disease of the central nervous
system. Foxp3+ regulatory T (Treg) cells are reduced in frequency and dysfunctional in …
system. Foxp3+ regulatory T (Treg) cells are reduced in frequency and dysfunctional in …
Platelet-derived microvesicles in cardiovascular diseases
Microvesicles (MVs) circulating in the blood are small vesicles (100–1,000 nm in diameter)
derived from membrane blebs of cells such as activated platelets, endothelial cells, and …
derived from membrane blebs of cells such as activated platelets, endothelial cells, and …
Extracellular vesicles: mediators and biomarkers of pathology along CNS barriers
Extracellular vesicles (EVs) are heterogeneous, nano-sized vesicles that are shed into the
blood and other body fluids, which disperse a variety of bioactive molecules (eg, protein …
blood and other body fluids, which disperse a variety of bioactive molecules (eg, protein …
Beyond macromolecules: extracellular vesicles as regulators of inflammatory diseases
Inflammation is the defense mechanism of the immune system against harmful stimuli such
as pathogens, toxic compounds, damaged cells, radiation, etc., and is characterized by …
as pathogens, toxic compounds, damaged cells, radiation, etc., and is characterized by …
Cerebrospinal fluid extracellular vesicle enrichment for protein biomarker discovery in neurological disease; multiple sclerosis
The discovery of disease biomarkers, along with the use of “liquid biopsies” as a minimally
invasive source of biomarkers, continues to be of great interest. In inflammatory diseases of …
invasive source of biomarkers, continues to be of great interest. In inflammatory diseases of …
Extracellular vesicles: current analytical techniques for detection and quantification
Since their first observation, understanding the biology of extracellular vesicles (EV) has
been an important and challenging field of study. They play a key role in the intercellular …
been an important and challenging field of study. They play a key role in the intercellular …
Extracellular vesicles in neuroinflammation: Pathogenesis, diagnosis, and therapy
J Ruan, X Miao, D Schlüter, L Lin, X Wang - Molecular Therapy, 2021 - cell.com
Extracellular vesicles (EVs) are bilayer membrane vesicles and act as key messengers in
intercellular communication. EVs can be secreted by both neurons and glial cells in the …
intercellular communication. EVs can be secreted by both neurons and glial cells in the …