Purpose Cardiac autonomic neuropathy (CAN) is a serious complication of type 1 and type 2
diabetes and is independently associated with major cardiovascular events, morbidity, and …

Introduction Corneal confocal microscopy (CCM) is a rapid non‐invasive ophthalmic
imaging technique that identifies corneal nerve fiber damage. Small studies suggest that …

Nerve conduction studies (NCS) are an essential aspect of the assessment of patients with
peripheral neuropathies. However, conventional NCS do not reflect activation of small …

A biomarker is a “characteristic that is measured as an indicator of normal biological
processes, pathogenic processes, or responses to an exposure or intervention, including …

Distal symmetric polyneuropathy (DPN), particularly chronic sensorimotor DPN, represents
one of the most frequent complications of diabetes, affecting 50% of diabetic patients and …

The cornea's intense innervation is responsible for corneal trophism and ocular surface
hemostasis maintenance. Corneal diabetic neuropathy affects subbasal nerve plexus, with …

Purpose There has been increasing interest in identifying non-invasive, imaging biomarkers
for neurodegenerative disorders of the central nervous system (CNS). The aim of this proof …

Diabetic peripheral neuropathy (DPN) is a serious complication of diabetes, where skin
biopsy assessing intraepidermal nerve fiber density (IENFD) plays an important diagnostic …

The study investigated the diagnostic performance for diabetic cardiovascular autonomic
neuropathy (CAN) and diabetic polyneuropathy (DPN) of the combined use of composite …

Diabetic peripheral neuropathy (DPN) is a common complication of diabetes mellitus (DM).
The typical manifestation is a length-dependent “glove and sock” sensation. At present …