Extracellular vesicles (EVs), including exosomes, are increasingly recognized as potent
mediators of intercellular communication due to their capacity to transport a diverse array of …

Extracellular vesicles (EVs) are small, membrane-bound structures that are released from
cells into the surrounding environment. These structures can be categorized as exosomes …

Extracellular vesicles (EVs) are gaining increasing attention for diagnostic and therapeutic
applications in various diseases. These natural nanoparticles benefit from favorable safety …

RNA-based therapeutics have shown great promise in treating a broad spectrum of
diseases through various mechanisms including knockdown of pathological genes …

Over the past decades, a multitude of synthetic drug delivery systems has been developed
and introduced to the market. However, applications of such systems are limited due to …

Circular RNA (circRNA) is a novel member of the noncoding cancer genome with distinct
properties and diverse cellular functions, which is being explored at a steadily increasing …

In recent years, a large number of circRNAs have been identified in mammalian cells with
high-throughput sequencing technologies and bioinformatics. The aberrant expression of …

Gliomas are complex and heterogeneous brain tumors with poor prognosis. Glioma cells
can communicate with their surroundings to create a tumor-permissive microenvironment …

Exosomes are small extracellular vesicles that contain genetic material, proteins, and lipids.
They function as potent signaling molecules between cancer cells and the surrounding cells …

Despite the multiple ongoing and novel initiatives for develo** brain-targeted drug
delivery systems, insurmountable obstacles remain. A perfect drug delivery device that can …