Signaling pathways and therapeutic interventions in gastric cancer
ZN Lei, QX Teng, Q Tian, W Chen, Y ** the genomic diaspora of gastric cancer
Gastric cancer (GC) is a leading contributor to global cancer incidence and mortality.
Pioneering genomic studies, focusing largely on primary GCs, revealed driver alterations in …
Pioneering genomic studies, focusing largely on primary GCs, revealed driver alterations in …
Multi-ancestry genome-wide association analyses improve resolution of genes and pathways influencing lung function and chronic obstructive pulmonary disease risk
Lung-function impairment underlies chronic obstructive pulmonary disease (COPD) and
predicts mortality. In the largest multi-ancestry genome-wide association meta-analysis of …
predicts mortality. In the largest multi-ancestry genome-wide association meta-analysis of …
Characterizing dedifferentiation of thyroid cancer by integrated analysis
Understanding of dedifferentiation, an indicator of poo prognosis for patients with thyroid
cancer, has been hampered by imprecise and incomplete characterization of its …
cancer, has been hampered by imprecise and incomplete characterization of its …
Molecular pathogenesis, targeted therapies, and future perspectives for gastric cancer
Gastric cancer is a major source of global cancer mortality with limited treatment options and
poor patient survival. As our molecular understanding of gastric cancer improves, we are …
poor patient survival. As our molecular understanding of gastric cancer improves, we are …
[HTML][HTML] Comprehensive clinical and molecular characterization of claudin 18.2 expression in advanced gastric or gastroesophageal junction cancer
Y Kubota, A Kawazoe, S Mishima, Y Nakamura… - ESMO open, 2023 - Elsevier
Background We conducted comprehensive clinical and molecular characterization of
claudin 18.2 expression (CLDN18. 2) in advanced gastric or gastroesophageal junction …
claudin 18.2 expression (CLDN18. 2) in advanced gastric or gastroesophageal junction …
Claudins and gastric cancer: an overview
I Hashimoto, T Oshima - Cancers, 2022 - mdpi.com
Simple Summary Gastric cancer (GC) is one of the most common cancers and the third
leading cause of cancer deaths worldwide, with a high frequency of recurrence and …
leading cause of cancer deaths worldwide, with a high frequency of recurrence and …
Comprehensive genomic and epigenomic analysis in cancer of unknown primary guides molecularly-informed therapies despite heterogeneity
L Möhrmann, M Werner, M Oleś, A Mock… - Nature …, 2022 - nature.com
The benefit of molecularly-informed therapies in cancer of unknown primary (CUP) is
unclear. Here, we use comprehensive molecular characterization by whole genome/exome …
unclear. Here, we use comprehensive molecular characterization by whole genome/exome …
Gain-of-Function RHOA Mutations Promote Focal Adhesion Kinase Activation and Dependency in Diffuse Gastric Cancer
Diffuse gastric cancer (DGC) is a lethal malignancy lacking effective systemic therapy.
Among the most provocative recent results in DGC has been that of highly recurrent …
Among the most provocative recent results in DGC has been that of highly recurrent …
Gastric cancer and genomics: review of literature
T Onoyama, S Ishikawa, H Isomoto - Journal of Gastroenterology, 2022 - Springer
Gastric cancer (GC) is a major health concern in many countries. GC is a heterogeneous
disease stratified by histopathological differences. However, these variations are not used to …
disease stratified by histopathological differences. However, these variations are not used to …