Signaling pathways and therapeutic interventions in gastric cancer

ZN Lei, QX Teng, Q Tian, W Chen, Y ** the genomic diaspora of gastric cancer
KG Yeoh, P Tan - Nature reviews cancer, 2022 - nature.com
Gastric cancer (GC) is a leading contributor to global cancer incidence and mortality.
Pioneering genomic studies, focusing largely on primary GCs, revealed driver alterations in …

Characterizing dedifferentiation of thyroid cancer by integrated analysis

H Luo, X **a, GD Kim, Y Liu, Z Xue, L Zhang, Y Shu… - Science …, 2021 - science.org
Understanding of dedifferentiation, an indicator of poo prognosis for patients with thyroid
cancer, has been hampered by imprecise and incomplete characterization of its …

[HTML][HTML] Claudins and gastric cancer: an overview

I Hashimoto, T Oshima - Cancers, 2022 - mdpi.com
Simple Summary Gastric cancer (GC) is one of the most common cancers and the third
leading cause of cancer deaths worldwide, with a high frequency of recurrence and …

The role and mechanism of claudins in cancer

DW Wang, WH Zhang, G Danil, K Yang, JK Hu - Frontiers in Oncology, 2022 - frontiersin.org
Claudins are a tetraspan membrane protein multigene family that plays a structural and
functional role in constructing tight junctions. Claudins perform crucial roles in maintaining …

Targeting CLDN18. 2 in cancers of the gastrointestinal tract: new drugs and new indications

J Chen, Z Xu, C Hu, S Zhang, M Zi, L Yuan… - Frontiers in …, 2023 - frontiersin.org
Cancers of the gastrointestinal (GI) tract greatly contribute to the global cancer burden and
cancer-related death. Claudin-18.2 (CLDN18. 2), a transmembrane protein, is a major …