The terms MSC and MSCs have become the preferred acronym to describe a cell and a cell
population of multipotential stem/progenitor cells commonly referred to as mesenchymal …

Adult skeletal muscle in mammals is a stable tissue under normal circumstances but has
remarkable ability to repair after injury. Skeletal muscle regeneration is a highly orchestrated …

The immune system plays a central role in tissue repair and regeneration. Indeed, the
immune response to tissue injury is crucial in determining the speed and the outcome of the …

Fibroblasts synthesize the extracellular matrix of connective tissue and play an essential role
in maintaining the structural integrity of most tissues. Researchers have long suspected that …

Following their discovery in 1961, it was speculated that satellite cells were dormant
myoblasts, held in reserve until required for skeletal muscle repair. Evidence for this …

Pericytes are widely believed to function as mesenchymal stem cells (MSCs), multipotent
tissue-resident progenitors with great potential for regenerative medicine. Cultured pericytes …

Chronic diseases confer tissue and organ damage that reduce quality of life and are largely
refractory to therapy. Although stem cells hold promise for treating degenerative diseases …

Adult tissue repair and regeneration require stem-progenitor cells that can self-renew and
generate differentiated progeny. Skeletal muscle regenerative capacity relies on muscle …

Bone has the unique capacity to heal without the formation of a fibrous scar, likely because
several of the cellular and molecular processes governing bone healing recapitulate the …

Generating human skeletal muscle models is instrumental for investigating muscle
pathology and therapy. Here, we report the generation of three-dimensional (3D) artificial …