Homeobox genes and the specification of neuronal identity
O Hobert - Nature Reviews Neuroscience, 2021 - nature.com
The enormous diversity of cell types that characterizes any animal nervous system is defined
by neuron-type-specific gene batteries that endow cells with distinct anatomical and …
by neuron-type-specific gene batteries that endow cells with distinct anatomical and …
Data incompleteness may form a hard-to-overcome barrier to decoding life's mechanism
L Kondratyeva, I Alekseenko, I Chernov, E Sverdlov - Biology, 2022 - mdpi.com
Simple Summary The influence of data incompleteness on the correctness of conclusions
about the structure and functions of the objects under study is widely discussed in the …
about the structure and functions of the objects under study is widely discussed in the …
The enteric nervous system of the C. elegans pharynx is specified by the Sine oculis-like homeobox gene ceh-34
Overarching themes in the terminal differentiation of the enteric nervous system, an
autonomously acting unit of animal nervous systems, have so far eluded discovery. We …
autonomously acting unit of animal nervous systems, have so far eluded discovery. We …
Neuronal birthdate reveals topography in a vestibular brainstem circuit for gaze stabilization
Across the nervous system, neurons with similar attributes are topographically organized.
This topography reflects developmental pressures. Oddly, vestibular (balance) nuclei are …
This topography reflects developmental pressures. Oddly, vestibular (balance) nuclei are …
Widespread employment of conserved C. elegans homeobox genes in neuronal identity specification
Homeobox genes are prominent regulators of neuronal identity, but the extent to which their
function has been probed in animal nervous systems remains limited. In the nematode …
function has been probed in animal nervous systems remains limited. In the nematode …
Cell context-dependent CFI-1/ARID3 functions control neuronal terminal differentiation
AT-rich interaction domain 3 (ARID3) transcription factors are expressed in the nervous
system, but their mechanisms of action are largely unknown. Here, we provide, in vivo, a …
system, but their mechanisms of action are largely unknown. Here, we provide, in vivo, a …
Nematode nuclear receptors as integrators of sensory information
More than 20 years ago, the sequencing of the genome of the nematode Caenorhabditis
elegans uncovered a still unparalleled abundance of C4-zinc finger orphan nuclear …
elegans uncovered a still unparalleled abundance of C4-zinc finger orphan nuclear …
Dietary E. coli promotes age-dependent chemotaxis decline in C. elegans
N Suryawinata, R Yokosawa, KHC Tan, AL Lai… - Scientific Reports, 2024 - nature.com
An animal's ability to sense odors declines during aging, and its olfactory drive is tuned by
internal states such as satiety. However, whether internal states modulate an age …
internal states such as satiety. However, whether internal states modulate an age …
CFI-1 functions unilaterally to restrict gap junction formation in C. elegans
Z Wu, L Pang, M Ding - Development, 2025 - journals.biologists.com
Electrical coupling is vital to neural communication, facilitating synchronized activity among
neurons. Despite its significance, the precise mechanisms governing the establishment of …
neurons. Despite its significance, the precise mechanisms governing the establishment of …
Nuclear factor Y is a pervasive regulator of neuronal gene expression
P Moreira, P Papatheodorou, S Deng, S Gopal… - Cell Reports, 2023 - cell.com
Nervous system function relies on the establishment of complex gene expression programs
that provide neuron-type-specific and core pan-neuronal features. These complementary …
that provide neuron-type-specific and core pan-neuronal features. These complementary …