Despite considerable advances in microsurgical techniques over the past decades, bone
tissue remains a challenging arena to obtain a satisfying functional and structural restoration …

Several synthetic scaffolds are being developed using polymers, ceramics and their
composites to overcome the limitations of auto-and allografts. Polymer–ceramic composites …

Type I collagen and nanocrystalline-substituted hydroxyapatite are the major components of
a natural composite—bone tissue. Both of these materials also play a significant role in …

The increase in osteoporotic fracture worldwide is urging bone tissue engineering research
to find new, improved solutions both for the biomaterials used in designing bone scaffolds …

The synthesis of collagen–hydroxyapatite composites has been carried out, and the
biocompatibility and osteoconductivity properties have been tested. This research was …

This paper presents a new way to obtain collagen/hydroxyapatite (COLL/HA) composite
materials by 3D printing. Because of high tendency of segregation of COLL/HA composite …

The use of methacrylic acid (MAA) in medicine was poorly investigated in the past but can
be of great importance because the incorporation of hydroxyapatite (HA) can lead to new …

BACKGROUND: Managing massive bone defects, a great challenge to orthopaedics
reconstructive surgery. The problem arise is the supply of suitable bone is limited with many …

Nanocomposites for Musculoskeletal Tissue Regeneration discusses the advanced
biomaterials scientists are exploring for use as tools to mimic the structure of …

Advances in tissue engineering and regenerative medicine have provided alternate
solutions for providing bone substitutes for bone and joint disease treatment. The tissue …